A Novel Microwave Sensor to Detect Specific Biomarkers in Human Cerebrospinal Fluid and Their Relationship to Cellular Ischemia During Thoracoabdominal Aortic Aneurysm Repair
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作者:
Fok, M.
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Liverpool Heart & Chest Hosp, Thorac Aort Aneurysm Serv, Liverpool L14 3PE, Merseyside, England
Liverpool John Moores Univ, Built Environm & Sustainable Technol BEST Res Ins, RF & Microwave Res Grp, Liverpool L3 2ET, Merseyside, EnglandLiverpool Heart & Chest Hosp, Thorac Aort Aneurysm Serv, Liverpool L14 3PE, Merseyside, England
Fok, M.
[1
,2
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Bashir, M.
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Liverpool Heart & Chest Hosp, Thorac Aort Aneurysm Serv, Liverpool L14 3PE, Merseyside, EnglandLiverpool Heart & Chest Hosp, Thorac Aort Aneurysm Serv, Liverpool L14 3PE, Merseyside, England
Bashir, M.
[1
]
Fraser, H.
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Liverpool Heart & Chest Hosp, Thorac Aort Aneurysm Serv, Liverpool L14 3PE, Merseyside, EnglandLiverpool Heart & Chest Hosp, Thorac Aort Aneurysm Serv, Liverpool L14 3PE, Merseyside, England
Fraser, H.
[1
]
Strouther, N.
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Liverpool Heart & Chest Hosp, Thorac Aort Aneurysm Serv, Liverpool L14 3PE, Merseyside, EnglandLiverpool Heart & Chest Hosp, Thorac Aort Aneurysm Serv, Liverpool L14 3PE, Merseyside, England
Strouther, N.
[1
]
Mason, A.
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Liverpool Heart & Chest Hosp, Thorac Aort Aneurysm Serv, Liverpool L14 3PE, Merseyside, EnglandLiverpool Heart & Chest Hosp, Thorac Aort Aneurysm Serv, Liverpool L14 3PE, Merseyside, England
Mason, A.
[1
]
机构:
[1] Liverpool Heart & Chest Hosp, Thorac Aort Aneurysm Serv, Liverpool L14 3PE, Merseyside, England
[2] Liverpool John Moores Univ, Built Environm & Sustainable Technol BEST Res Ins, RF & Microwave Res Grp, Liverpool L3 2ET, Merseyside, England
Thoraco-abdominal aneurysms (TAAA) represents a particularly lethal vascular disease that without surgical repair carries a dismal prognosis. However, there is an inherent risk from surgical repair of spinal cord ischaemia that can result in paraplegia. One method of reducing this risk is cerebrospinal fluid (CSF) drainage. We believe that the CSF contains clinically significant biomarkers that can indicate impending spinal cord ischaemia. This work therefore presents a novel measurement method for proteins, namely albumin, as a precursor to further work in this area. The work uses an interdigitated electrode (IDE) sensor and shows that it is capable of detecting various concentrations of albumin (from 0 to 100 g/L) with a high degree of repeatability at 200 MHz (R-2=0.991) and 4 GHz (R-2=0.975).
机构:
Univ Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USAUniv Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USA
Huynh, TTT
Miller, CC
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Univ Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USAUniv Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USA
Miller, CC
Estrera, AL
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Univ Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USAUniv Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USA
Estrera, AL
Mohamed, SG
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Univ Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USAUniv Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USA
Mohamed, SG
Hassoun, HT
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Univ Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USAUniv Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USA
Hassoun, HT
Sheinbaum, R
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Univ Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USAUniv Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USA
Sheinbaum, R
Porat, EE
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Univ Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USAUniv Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USA
Porat, EE
Safi, HJ
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Univ Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USAUniv Texas, Houston Med Sch, Mem Hermann Hosp, Dept Cardiothorac & Vasc Surg, Houston, TX 77030 USA
机构:
Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, ItalyUniv Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, Italy
Tshomba, Yamume
Leopardi, Marco
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Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, ItalyUniv Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, Italy
Leopardi, Marco
Mascia, Daniele
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Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, ItalyUniv Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, Italy
Mascia, Daniele
Kahlberg, Andrea
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Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, ItalyUniv Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, Italy
Kahlberg, Andrea
Carozzo, Andrea
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Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Via Olgettina 60, I-20132 Milan, ItalyUniv Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, Italy
Carozzo, Andrea
Magrin, Silvio
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Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Dept Anesthesia & Intens Care, Via Olgettina 60, I-20132 Milan, ItalyUniv Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, Italy
Magrin, Silvio
Melissano, Germano
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Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, ItalyUniv Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, Italy
Melissano, Germano
Chiesa, Roberto
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Univ Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, ItalyUniv Vita Salute San Raffaele, San Raffaele Sci Inst, Vasc Surg Unit, Via Olgettina 60, I-20132 Milan, Italy
机构:
Univ Ulsan, Coll Med, Asan Med Ctr, Dept Anesthesiol, Seoul 138736, South Korea
Univ Ulsan, Coll Med, Asan Med Ctr, Dept Pain Med, Seoul 138736, South KoreaUniv Ulsan, Coll Med, Asan Med Ctr, Dept Anesthesiol, Seoul 138736, South Korea
Jeong, Y. B.
Choi, W. J.
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Univ Ulsan, Coll Med, Asan Med Ctr, Dept Anesthesiol, Seoul 138736, South Korea
Univ Ulsan, Coll Med, Asan Med Ctr, Dept Pain Med, Seoul 138736, South KoreaUniv Ulsan, Coll Med, Asan Med Ctr, Dept Anesthesiol, Seoul 138736, South Korea
Choi, W. J.
Han, S. H.
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Cheongju St Marys Hosp, Cheongju, South KoreaUniv Ulsan, Coll Med, Asan Med Ctr, Dept Anesthesiol, Seoul 138736, South Korea
Han, S. H.
Choi, I. C.
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Univ Ulsan, Coll Med, Asan Med Ctr, Dept Anesthesiol, Seoul 138736, South Korea
Univ Ulsan, Coll Med, Asan Med Ctr, Dept Pain Med, Seoul 138736, South KoreaUniv Ulsan, Coll Med, Asan Med Ctr, Dept Anesthesiol, Seoul 138736, South Korea