The growth receptors and their role in wound healing

被引：0
作者：
Rolfe, Kerstin J. [1 ]
Grobbelaar, Adriaan O. [1 ]
机构：
[1] Royal Free Hosp, Inst Plast Surg Res & Educ, London NW3 2QG, England
来源：
CURRENT OPINION IN INVESTIGATIONAL DRUGS | 2010年 / 11卷 / 11期
关键词：
Chronic wound; growth factor; growth factor receptor; receptor tyrosine kinase; scarring; wound healing; STELLATE CELL ACTIVATION; FACTOR-BETA; EXTRACELLULAR-MATRIX; LUNG FIBROSIS; SOLUBLE BETAGLYCAN; HYPERTROPHIC SCAR; MESSENGER-RNA; IN-VITRO; SKIN; FIBROBLAST;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Abnormal wound healing is a major problem in healthcare today, with both scarring and chronic wounds affecting large numbers of individuals worldwide. Wound healing is a complex process involving several variables, including growth factors and their receptors. Chronic wounds fail to complete the wound healing process, while scarring is considered to be an overzealous wound healing process. Growth factor receptors and their ligands are being investigated to assess their potential in the development of therapeutic strategies to improve wound healing. This review discusses potential therapeutics for manipulating growth factors and their corresponding receptors for the treatment of abnormal wound healing.
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页码：1221 / 1228
页数：8
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