Pharmacologic Intervention for Osteoarthritis in Older Adults

被引：12

作者：

Harvey, William F. ^{[1
,2
]}

Hunter, David J. ^{[2
,3
]}

机构：

[1] Tufts Med Ctr, Div Rheumatol, Boston, MA 02111 USA

[2] New England Baptist Hosp, Div Res, Boston, MA USA

[3] Univ Sydney, Dept Rheumatol, No Clin Sch, Sydney, NSW 2065, Australia

来源：

CLINICS IN GERIATRIC MEDICINE | 2010年 / 26卷 / 03期

关键词：

Osteoarthritis; Geriatric; Pharmacology management; NONSTEROIDAL ANTIINFLAMMATORY DRUGS; INTRAARTICULAR HYALURONIC-ACID; DICLOFENAC SODIUM GEL; DOUBLE-BLIND; KNEE OSTEOARTHRITIS; TOPICAL CAPSAICIN; RHEUMATOID-ARTHRITIS; STANDING-COMMITTEE; CLINICAL-TRIALS; CARTILAGE LOSS;

D O I：

10.1016/j.cger.2010.03.008

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

The management of osteoarthritis requires a careful combination of pharmacologic and nonpharmacologic therapies to effect improvements in pain and function. When choosing pharmacologic therapy, the potential toxicities must be considered relative to potential benefits. This review highlights commonly used medications and presents the evidence for their effectiveness as well as their toxicities. Acetaminophen and nonsteroidal antiinflammatory drugs are the mainstay of pharmacologic therapy, but there are numerous adjunctive or alternative medications that may provide some benefit to patients with osteoarthritis.

引用

页码：503 / +

页数：14

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