Optimizing fat oxidation through exercise in severely obese Caucasian adolescents

被引:39
作者
Lazzer, Stefano
Busti, Carlo
Agosti, Fiorenza
De Col, Alessandra
Pozzo, Renzo
Sartorio, Alessandro
机构
[1] Ist Auxologico Italiano, Inst Ricovero Cura Carattere Sci, Lab Sperimentale Ric Auxo Endocrinol, I-20145 Milan, Italy
[2] IRCCS, Italian Inst Auxol, Div Auxol, Milan, Italy
[3] Univ Udine, Dept Biomed Sci & Technol, I-33100 Udine, Italy
关键词
D O I
10.1111/j.1365-2265.2007.02929.x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective To measure the contribution of substrate oxidation to energy expenditure during cycling at different workloads and to identify the exercise intensity that elicits the maximum fat oxidation rate in groups of severely obese or nonobese Caucasian adolescents. Design A total of 30 severely obese subjects (mean body mass index, BMI = 34.7 kg/m(2); fat-mass = 39.9%) and 30 nonobese sedentary adolescents (mean BMI = 22.7 kg/m(2); fat-mass = 21.8%) aged 14-16 years, participated in this study. Body composition was assessed by bioelectrical impedance. Peak oxygen uptake (VO(2)peak) and maximal fat oxidation rate were determined with indirect calorimetry by using a graded exercise test on an electromagnetically braked cycle ergometer. Results Predicted VO(2)max were expressed in absolute (l/min) and relative (ml/kg FFM/min) values, and maximal work rates were not significantly different between obese and nonobese adolescents, but were significantly higher in boys than in girls. No significant differences in fat oxidation rates were found in obese and nonobese sedentary adolescents during the graded exercise test. Maximal fat oxidation was observed at an exercise intensity corresponding to (mean +/- SD) 41 +/- 3% VO(2)max or 58 +/- 3% HRmax. At this exercise intensity, fat oxidation rates were higher in boys than in girls (0.32 +/- 0.02 g/min vs. 0.25 +/- 0.02 g/min, P < 0.001). Conclusions Severely obese and sedentary nonobese adolescents reached maximal fat oxidation rates at 41% VO(2)max, which corresponds to 58% HRmax. At this exercise intensity, fat oxidation rates were higher in boys than in girls probably due to higher VO(2)max and absolute workload during the exercise steps for boys compared with those for girls.
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页码:582 / 588
页数:7
相关论文
共 35 条
[1]   Optimizing fat oxidation through exercise and diet [J].
Achten, J ;
Jeukendrup, AE .
NUTRITION, 2004, 20 (7-8) :716-727
[2]   Determination of the exercise intensity that elicits maximal fat oxidation [J].
Achten, J ;
Gleeson, M ;
Jeukendrup, AE .
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 2002, 34 (01) :92-97
[3]  
*AM COLL SPORTS ME, 1995, GUID EX TEST PRESCR
[4]   BETA-ADRENERGIC STIMULATION OF SKELETAL-MUSCLE METABOLISM IN RELATION TO WEIGHT-REDUCTION IN OBESE MEN [J].
BLAAK, EE ;
VANBAAK, MA ;
KEMERINK, GJ ;
PAKBIERS, MTW ;
HEIDENDAL, GAK ;
SARIS, WHM .
AMERICAN JOURNAL OF PHYSIOLOGY, 1994, 267 (02) :E316-E322
[5]   Comparison of the type of substrate oxidation during exercise between pre and post pubertal markedly obese boys [J].
Brandou, F. ;
Savy-Pacaux, A. M. ;
Marie, J. ;
Brun, J. F. ;
Mercier, J. .
INTERNATIONAL JOURNAL OF SPORTS MEDICINE, 2006, 27 (05) :407-414
[6]   Effects of a two-month rehabilitation program on substrate utilization during exercise in obese adolescents [J].
Brandou, F ;
Dumortier, M ;
Garandeau, P ;
Mercier, J ;
Brun, JF .
DIABETES & METABOLISM, 2003, 29 (01) :20-27
[7]   Italian cross-sectional growth charts for height, weight and BMI (6-20y) [J].
Cacciari, E ;
Milani, S ;
Balsamo, A ;
Dammacco, F ;
De Luca, F ;
Chiarelli, F ;
Pasquino, AM ;
Tonini, G ;
Vanelli, M .
EUROPEAN JOURNAL OF CLINICAL NUTRITION, 2002, 56 (02) :171-180
[8]   SKELETAL-MUSCLE UTILIZATION OF FREE FATTY-ACIDS IN WOMEN WITH VISCERAL OBESITY [J].
COLBERG, SR ;
SIMONEAU, JA ;
THAETE, FL ;
KELLEY, DE .
JOURNAL OF CLINICAL INVESTIGATION, 1995, 95 (04) :1846-1853
[9]   Skeletal muscle low attenuation area and maximal fat oxidation rate during submaximal exercise in male obese individuals [J].
Dériaz, O ;
Dumont, M ;
Bergeron, N ;
Després, JP ;
Brochu, M ;
Prud'homme, D .
INTERNATIONAL JOURNAL OF OBESITY, 2001, 25 (11) :1579-1584
[10]  
Dietz WH, 1998, PEDIATRICS, V101, P518