Comorbid addictive disorders and schizophrenia in the aspect of pathogenesis and treatment

被引:0
作者
Eryshev, O. F. [1 ]
Arkad'ev, V. V. [1 ]
机构
[1] VM Bekhterev Psychoneurol Res Inst, St Petersburg, Russia
关键词
addictive disorders; schizophrenia; comorbidity; biochemical mechanisms; neuroleptics; SUBSTANCE USE DISORDERS; NMDA RECEPTOR HYPOFUNCTION; PREFRONTAL CORTEX; DOPAMINE SYSTEM; WORKING-MEMORY; CANNABIS USE; DRUG-ABUSE; ALCOHOL; CLOZAPINE; GLUTAMATE;
D O I
暂无
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Combinations of schizophrenia with addictive disorders are common in clinical practice. Some hypotheses were posited to explain this phenomenon with the biochemical hypothesis being the most common. A vast body of evidence supports the similarity in the pathogenesis of addiction and schizophrenia. Biochemical data on the pathogenesis of both diseases are used for treatment recommendations. However there are many discrepancies in this field and future research is needed.
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页码:67 / 73
页数:7
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