Pegylation of 1,4,8,11-tetraazacyclotetradecane (cyclam) and its Cu(II) complexation

被引：17

作者：

Stephan, H

Geipel, G

Appelhans, D

Bernhard, G

Tabuani, D

Komber, H

Voit, B

机构：

[1] Res Ctr Rossendorf Inc, Inst Radiochem, D-01328 Dresden, Germany

[2] Res Ctr Rossendorf Inc, Inst Bioinorgan & Radiopharmaceut Chem, D-01328 Dresden, Germany

[3] Inst Polymer Res Dresden, D-01069 Dresden, Germany

来源：

TETRAHEDRON LETTERS | 2005年 / 46卷 / 18期

关键词：

cyclam; synthesis; complex formation; fluorescence;

D O I：

10.1016/j.tetlet.2005.03.051

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Two novel star-like cyclam derivatives appended with four amino groups and four PEG-arms have been synthesised. The complex formation of cyclam and the two cyclam derivatives with Cu(II) has been studied by UV vis and time-resolved laserinduced fluorescence (TRLFS) measurements outlining 1:1 complexes between cyclam ligands and CU(II). By TRLFS measurements a quench effect of the CU(II) on the fluorescence of the ligand was also found to determine the complex formation between Cu(II) and the ligands. (c) 2005 Elsevier Ltd. All rights reserved.

引用

页码：3209 / 3212

页数：4

共 43 条

[1] Ultrafine selective metal-complexing nanoparticles: Synthesis by microemulsion copolymerization, binding capacity, and ligand accessibility [J].