Preparation and characterization of magnetic molecularly imprinted polymers for the extraction of hexamethylenetetramine in milk samples

被引：34

作者：

Xu, Xing ^{[1
,2
]}

Duhoranimana, Emmanuel ^{[1
]}

Zhang, Xiaoming ^{[1
]}

机构：

[1] Jiangnan Univ, Sch Food Sci & Technol, State Key Lab Food Sci & Technol, Wuxi 214122, Jiangsu, Peoples R China

[2] Dali Comprehens Inspect Ctr Qual & Tech Supervis, Dali 671000, Yunnan, Peoples R China

来源：

TALANTA | 2017年 / 163卷

关键词：

Hexamethylenetetramine; Magnetic molecularly imprinted polymers; Magnetic solid phase extraction; Milk; GC-MS/MS; SOLID-PHASE EXTRACTION; PERFORMANCE LIQUID-CHROMATOGRAPHY; MESOPOROUS SILICA MICROSPHERES; SELECTIVE EXTRACTION; PROTOCATECHUIC ACID; METHOD VALIDATION; AIDED-DESIGN; NANOPARTICLES; METHENAMINE; PLASMA;

D O I：

10.1016/j.talanta.2016.10.080

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Magnetic molecularly imprinted polymers (M-MIPs) were synthesized as the sorbents for extracting hexamethylenetetramine (HMT) from milk samples. Molecular simulations were used to calculate the interaction energies of the template monomers. The physical properties of M-MIPs were characterized. The adsorption isotherms and kinetics were investigated. Gas chromatography coupled with tandem mass spectrometry (GC-MS/MS) was applied to determine the amount of HMT residue in milk samples. In the optimized method, a linear calibration curve was obtained using a matrix-matched standard in the range of 1.0-50.0 mu g L-1. The limit of detection (LOD) and limit of quantification (LOQ) was 0.3 mu g kg(-1) and 1.0 mu g kg(-1), respectively. The relative standard deviation (RSD) of the intra-day assay ranged from 2.6% to 5.2%, while that of the inter-day assay ranged from 3.6% to 11.5%. The recovery of HMT in milk samples ranged from 88.7% to 111.4%.

引用

页码：31 / 38

页数：8

共 38 条

[1] Computational design of an enantioselective molecular imprinted polymer for the solid phase extraction of S-warfarin from plasma [J].