Chinese Herb Astragalus membranaceus Enhances Recovery of Hemorrhagic Stroke: Double-Blind, Placebo-Controlled, Randomized Study

被引:21
作者
Chen, Chun-Chung [2 ,3 ,4 ]
Lee, Han-Chung [2 ,3 ,4 ]
Chang, Ju-Hsin [5 ]
Chen, Shuang-Shuang [2 ]
Li, Tsai-Chung [6 ]
Tsai, Chang-Hai [4 ,7 ]
Cho, Der-Yang [2 ,4 ]
Hsieh, Ching-Liang [1 ,8 ,9 ]
机构
[1] China Med Univ, Coll Chinese Med, Grad Inst Acupuncture Sci, Taichung 40402, Taiwan
[2] China Med Univ Hosp, Dept Neurosurg, Taichung 40402, Taiwan
[3] China Med Univ, Coll Chinese Med, Inst Integrated Med, Taichung 40402, Taiwan
[4] China Med Univ, Coll Med, Sch Med, Taichung 40402, Taiwan
[5] China Med Univ Hosp, Dept Anesthesiol, Taichung 40402, Taiwan
[6] China Med Univ, Coll Publ Hlth, Grad Inst Biostat, Taichung 40402, Taiwan
[7] China Med Univ, Dept Pediat, Div Pediat Neurol, Taichung 40402, Taiwan
[8] China Med Univ, Acupuncture Res Ctr, Taichung 40402, Taiwan
[9] China Med Univ Hosp, Dept Chinese Med, Taichung 40402, Taiwan
关键词
EXPERIMENTAL INTRACEREBRAL HEMATOMA; C-REACTIVE PROTEIN; MANAGEMENT; MODEL; CARE; IV;
D O I
10.1155/2012/708452
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
We tested the effect of Astragalus membranaceus (AM) on acute hemorrhagic stroke. Seventy-eight patients were randomly assigned to Group A (3 g of AM three times/day for 14 days); or Group B (3 g of placebo herb). A total of 68 patients (Group A 36, Group B 32) completed the trial. The increase of functional independence measure scale score between baseline and week 4 was 24.53 +/- 23.40, and between baseline and week 12 was 34.69 +/- 28.89, in the Group A was greater than 11.97 +/- 11.48 and 23.94 +/- 14.8 in the Group B (both P <= 0.05). The increase of Glasgow outcome scale score between baseline and week 12 was 0.75 +/- 0.77 in the Group A was greater than 0.41 +/- 0.50 in the Group B (P < 0.05). The results are preliminary and need a larger study to assess the efficacy of AM after stroke.
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页数:11
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