Type 2 diabetes mellitus in children and adolescents

被引:44
作者
Marcovecchio, M [1 ]
Mohn, A [1 ]
Chiarelli, F [1 ]
机构
[1] Univ G dAnnunzio, Dept Pediat, I-66100 Chieti, Italy
关键词
T2DM; insulin resistance; children; adolescents; youth;
D O I
10.1007/BF03347581
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Over the last decade, there has been an alarming increase of Type 2 diabetes mellitus (T2DM) in youths, concomitant with the rise of obesity in this age group. T2DM is a progressive disease with a gradual increase in insulin resistance associated later with a decline in insulin secretion with fasting hyperglycemia. Prevalence of T2DM in children is mostly linked to some risk factors: obesity and sedentary lifestyle, puberty, membership of ethnic minorities, features of insulin resistance, family history of T2DM, female gender and perinatal factors. Prevention is essential and can be considered a public health approach directed to the general population. Treatment of T2DM in youth is complex and based on different strategies: diet, exercise and pharmacotherapy. An appropriated intervention program must be started early, in order to prevent or retard the progression of the disease and associated comorbidities.
引用
收藏
页码:853 / 863
页数:11
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