Regulation of Escherichia coli RNase III activity

被引：7

作者：

Lim, Boram ^{[1
]}

Sim, Minji ^{[1
]}

Lee, Howoon ^{[1
]}

Hyun, Seogang ^{[1
]}

Lee, Younghoon ^{[2
]}

Hahn, Yoonsoo ^{[1
]}

Shin, Eunkyoung ^{[3
]}

Lee, Kangseok ^{[1
]}

机构：

[1] Chung Ang Univ, Dept Life Sci, Seoul 156756, South Korea

[2] Korea Adv Inst Sci & Technol, Dept Chem, Taejon 305701, South Korea

[3] Chung Ang Univ, Coll Pharm, Seoul 156756, South Korea

来源：

JOURNAL OF MICROBIOLOGY | 2015年 / 53卷 / 08期

关键词：

RNase III; mRNA stability; regulator; catalytic mechanism; stress response; osmotic stress; DOUBLE-STRANDED-RNA; RIBOSOMAL PRECURSOR RNA; RIBONUCLEASE-III; MESSENGER-RNA; BIOFILM FORMATION; GENE-EXPRESSION; POLYNUCLEOTIDE PHOSPHORYLASE; BACILLUS-SUBTILIS; STRESS CONDITIONS; PROTEIN-KINASE;

D O I：

10.1007/s12275-015-5323-x

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Bacterial cells respond to changes in the environment by adjusting their physiological reactions. In cascades of cellular responses to stresses of various origins, rapid modulation of RNA function is known to be an effective biochemical adaptation. Among many factors affecting RNA function, RNase III, a member of the phylogenetically highly conserved endoribonuclease III family, plays a key role in posttranscriptional regulatory pathways in Escherichia coli. In this review, we provide an overview of the factors affecting RNase III activity in E. coli.

引用

页码：487 / 494

页数：8

共 58 条

[1] Escherichia coli ribonuclease III:: Affinity purification of hexahistidine-tagged enzyme and assays for substrate binding and cleavage [J].