Efficiency of Antibacterial Suture Material in Cardiac Surgery: A Double-Blind Randomized Prospective Study

被引:39
|
作者
Isik, Isil [1 ]
Selimen, Deniz [1 ]
Senay, Sahin [2 ]
Alhan, Cem [2 ]
机构
[1] Marmara Univ, Fac Hlth Sci, Surg Nursing Dept, Istanbul, Turkey
[2] Acibadem Univ, Sch Med, Dept Cardiovasc Surg, Istanbul, Turkey
来源
HEART SURGERY FORUM | 2012年 / 15卷 / 01期
关键词
SURGICAL-SITE INFECTIONS; RISK-FACTORS; LEG; RATES;
D O I
10.1532/HSF98.20111106
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Objective: Postoperative surgical site infections (SSI) still greatly affect mortality and morbidity in cardiovascular surgery. SSI may be related to the suture material. In this prospective, randomized, controlled, and double-blinded study, the effect of antibacterial suture material on SSI in cardiac surgical patients was investigated. Methods: We randomly allocated 510 patients into 2 groups. Antibacterial suture materials were used for wound closure in 170 patients (triclosan-coated suture group), and routine suture materials were used in 340 patients (noncoated suture group). All patients were evaluated for SSI on days 10, 20, and 30 following cardiac surgery. Results: Preoperative risk factors and laboratory findings were comparable for the 2 groups. Sternal infection occurred in 4 (2.4%) of the patients in the triclosan-coated suture group and in 3.5% of the noncoated suture group (P > .05). Leg wound infection occurred in 5 (3.5%) of the patients in the triclosan-coated suture group and in 3.8% of the noncoated suture group (P > .05). Only diabetes mellitus was an independent predictor of SSI. Conclusion: Both noncoated and triclosan-coated suture materials are safe. Larger studies may be needed to show the benefit and cost-effectiveness, if any, of triclosan-coated materials over noncoated materials.
引用
收藏
页码:E40 / E45
页数:6
相关论文
共 50 条
  • [1] DESMOPRESSIN ACETATE IN CARDIAC-SURGERY - A DOUBLE-BLIND, RANDOMIZED STUDY
    TEMECK, BK
    BACHENHEIMER, LC
    KATZ, NM
    COUGHLIN, SS
    WALLACE, RB
    SOUTHERN MEDICAL JOURNAL, 1994, 87 (06) : 611 - 615
  • [2] Tranexamic acid administration after cardiac surgery - A prospective, randomized, double-blind, placebo-controlled study
    Casati, V
    Bellotti, F
    Gerli, C
    Franco, A
    Oppizzi, M
    Cossolini, M
    Calori, G
    Benussi, S
    Alfieri, O
    Torri, G
    ANESTHESIOLOGY, 2001, 94 (01) : 8 - 14
  • [3] Treatment of pulmonary hypertension in patients undergoing cardiac surgery with cardiopulmonary bypass: a randomized, prospective, double-blind study
    Fattouch, Khalil
    Sbraga, Fabrizio
    Sampognaro, Roberta
    Bianco, Giuseppe
    Gucciardo, Marco
    Lavalle, Carlo
    Vizza, Carmine Dario
    Fedele, Francesco
    Ruvolo, Giovanni
    JOURNAL OF CARDIOVASCULAR MEDICINE, 2006, 7 (02) : 119 - 123
  • [4] The prospective, randomized, double-blind clinical trial in orthopaedic surgery
    Clark, CR
    JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1997, 79A (08): : 1119 - 1120
  • [5] A Prospective, Randomized, Double-Blind Trial of 3 Regimens for Sedation and Analgesia After Cardiac Surgery
    Oliver, William C., Jr.
    Nuttall, Gregory A.
    Murari, Terri
    Bauer, Lori K.
    Johnsrud, Kelly H.
    Long, Kirsten J. Hall
    Orszulak, Thomas A.
    Schaff, Hartzell V.
    Hanson, Andrew C.
    Schroeder, Darrell R.
    Ereth, Mark H.
    Abel, Martin D.
    JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 2011, 25 (01) : 110 - 119
  • [6] Tube placement: A prospective, randomized double-blind study
    Derkay, CS
    Wadsworth, JT
    Darrow, DH
    Strasnick, B
    Thompson, GK
    O'Master, J
    LARYNGOSCOPE, 1998, 108 (01): : 97 - 101
  • [7] Sedative effect of acupuncture during cataract surgery - Prospective randomized double-blind study
    Gioia, Luigi
    Cabrini, Luca
    Gemma, Marco
    Fiori, Rossana
    Fasce, Francesco
    Bolognesi, Gianluigi
    Spinelli, Alessandra
    Beretta, Luigi
    JOURNAL OF CATARACT AND REFRACTIVE SURGERY, 2006, 32 (11): : 1951 - 1954
  • [8] Optimal Position of Inferior Vena Cava Cannula in Pediatric Cardiac Surgery: A Prospective, Randomized, Controlled, Double-Blind Study
    Seino, Yutaka
    Ohashi, Nobuko
    Imai, Hidekazu
    Baba, Hiroshi
    JOURNAL OF CARDIOTHORACIC AND VASCULAR ANESTHESIA, 2019, 33 (05) : 1253 - 1259
  • [9] Dexmedetomidine as an adjunct in postoperative analgesia following cardiac surgery: A randomized, double-blind study
    Priye, Shio
    Jagannath, Sathyanarayan
    Shivaprakash, Dipali Singh S.
    Reddy, Durga Prasad
    SAUDI JOURNAL OF ANAESTHESIA, 2015, 9 (04) : 353 - 358
  • [10] RESULTS OF A PROSPECTIVE RANDOMIZED DOUBLE-BLIND TRIAL OF APROTININ IN COLONIC SURGERY
    YOUNG, HL
    WHEELER, MH
    CLARK, CG
    HAMPSON, LG
    WORLD JOURNAL OF SURGERY, 1984, 8 (03) : 367 - 373