FTIR spectroscopy characterization of poly (vinyl alcohol) hydrogel with different hydrolysis degree and chemically crosslinked with glutaraldehyde

被引：1443

作者：

Mansur, Herman S. ^{[1
]}

Sadahira, Carolina M. ^{[1
]}

Souza, Adriana N. ^{[1
]}

Mansur, Alexandra A. P. ^{[1
]}

机构：

[1] Univ Fed Minas Gerais, Dept Met & Mat Engn, BR-30160030 Belo Horizonte, MG, Brazil

来源：

MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS | 2008年 / 28卷 / 04期

关键词：

FTIR spectroscopy; hydrogel; crosslinking; PVA; hybrids;

D O I：

10.1016/j.msec.2007.10.088

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

In this work, poly (vinyl alcohol) (PVA) hydrogels with different degree of hydrolysis (DH) were prepared by chemical crosslinking with glutaraldehyde (GA). The nanostructure of the resulting hydrogels was investigated by Fourier Transform Infrared Spectroscopy (FTIR) and Synchrotron small-angle X-ray scattering characterization (SAXS). In vitro tests were performed by swelling ratio assays in different pH solutions. The infrared spectra of the crosslinked PVA showed absorption bands of the acetal bridges resulted from the reaction of the GA with the OH groups from PVA. Also the FTIR spectroscopy was used to determine the crystallinity of the PVA film based on the relative intensity of the vibration band at 1141 cm(-1). The results have showed an increase of hydrogel crystallinity with higher DH of PVA. SAXS patterns have clearly indicated important modifications on the PVA semicrystalline structure when it was crosslinked by GA. The swelling ratio was significantly reduced by chemically crosslinking the PVA network. PVA-derived hydrogel with chemically modified network was found to be pH-sensitive, indicating a high potential to be used in drug delivery polymer system. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：539 / 548

页数：10

共 34 条

[1] Controlled release of paraquat from poly vinyl alcohol hydrogel [J].

Alemzadeh, I ;

Vossoughi, M .

CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION, 2002, 41 (08) :707-710

[2] Design of novel hybrid organic-inorganic nanostructured biomaterials for immunoassay applications [J].

Andrade, G. ;

Barbosa-Stancioli, E. F. ;

Mansur, A. A. Piscitelli ;

Vasconcelos, W. L. ;

Mansur, H. S. .

BIOMEDICAL MATERIALS, 2006, 1 (04) :221-234

[3]

ANDRADE G, IN PRESS J MAT SCI

[4] Mechanisms of solute and drug transport in relaxing, swellable, hydrophilic glassy polymers [J].

Brazel, CS ;

Peppas, NA .

POLYMER, 1999, 40 (12) :3383-3398

[5]

Coates J., 2000, ENCY ANAL CHEM, P10815, DOI DOI 10.1002/9780470027318.A5606

[6] Structure and swelling of poly(acrylic acid) hydrogels: effect of pH, ionic strength, and dilution on the crosslinked polymer structure [J].

Elliott, JE ;

Macdonald, M ;

Nie, J ;

Bowman, CN .

POLYMER, 2004, 45 (05) :1503-1510

[7] Chemical and pH sensors based on the swelling behavior of hydrogels [J].

Gerlach, G ;

Guenther, M ;

Sorber, J ;

Suchaneck, G ;

Arndt, KF ;

Richter, A .

SENSORS AND ACTUATORS B-CHEMICAL, 2005, 111 :555-561

[8] Studies on the cross-linking of poly(vinyl alcohol) [J].

Gohil, JM ;

Bhattacharya, A ;

Ray, P .

JOURNAL OF POLYMER RESEARCH, 2006, 13 (02) :161-169

[9]

Hassan CM, 2000, ADV POLYM SCI, V153, P37

[10] Analysis of burst release of proxyphylline from poly(vinyl alcohol) hydrogels [J].

Huang, X ;

Brazel, CS .

CHEMICAL ENGINEERING COMMUNICATIONS, 2003, 190 (04) :519-532

← 1 2 3 4 →