Inclusion of CpG adjuvant with plasmid DNA coding for NcGRA7 improves protection against congenital neosporosis

被引：40

作者：

Jenkins, M ^{[1
]}

Parker, C

Tuo, W

Vinyard, B

Dubey, JP

机构：

[1] USDA, ARS, ANRI, Anim Parasit Dis Lab, Beltsville, MD 20705 USA

[2] USDA, ARS, Biometr Consulting Unit, Beltsville, MD 20705 USA

来源：

INFECTION AND IMMUNITY | 2004年 / 72卷 / 03期

关键词：

D O I：

10.1128/IAI.72.3.1817-1819.2004

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The present study showed that incorporation of CpG adjuvant into plasmid DNA coding for NcGRA7 antigen resulted in a twofold increase in the level of protection against congenital transfer of Neospora caninum. The level of protection was considerably higher than that observed in pups born from dams immunized with nonrecombinant plasmid.

引用

页码：1817 / 1819

页数：3

共 21 条

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