The morphology of GM1x/SM0.6-x/Chol0.4 planar bilayers supported on SiO2 surfaces

被引：15

作者：

Mao, Yanli ^{[1
,2
]}

Tero, Ryugo ^{[1
,3
]}

Imai, Yosuke ^{[4
]}

Hoshino, Tyuji ^{[4
]}

Urisu, Tsuneo ^{[1
,3
]}

机构：

[1] Inst Mol Sci, Dept Life & Coordinat Complex Mol Sci, Okazaki, Aichi 4448585, Japan

[2] Henan Univ, Dept Phys, Kaifeng 475001, Peoples R China

[3] Grad Univ Adv Studies, Okazaki, Aichi 4448585, Japan

[4] Chiba Univ, Dept Phys Chem, Chiba 2638522, Japan

来源：

CHEMICAL PHYSICS LETTERS | 2008年 / 460卷 / 1-3期

基金：

日本学术振兴会;

关键词：

D O I：

10.1016/j.cplett.2008.05.097

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Ganglioside GM1 (GM1), sphingomyelin (SM) and cholesterol (Chol) are dominant lipid components of rafts in plasma membranes. The morphology of GM1(x)/SM(0.6) (x)/Chol(0.4) SPBs on SiO(2) surfaces has been studied by atomic force microscopy and fluorescence microscopy at various ratios of GM1/SM (x = 0-0.25). The unique changes in morphology depending on the GM1 concentrations are qualitatively explained by hydrogen bonding and the hydrophobic interactions between SM and Chol, and by hydrogen bonding and the steric effects between bulky GM1 headgroups under Ca(2+) existing conditions and the electrostatic repulsion between the negative charges of GM1 headgroups under Ca(2+) nonexisting conditions. (C) 2008 Elsevier B.V. All rights reserved.

引用

页码：289 / 294

页数：6

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