Clinical utility of clodronate in the prevention and management of osteoporosis in patients intolerant of oral bisphosphonates

被引：15
|
作者：
Muratore, Maurizio [1 ]
Quarta, Eugenio [1 ]
Grimaldi, Antonella [1 ]
Calcagnile, Fabio [1 ]
Quarta, Laura [1 ]
机构：
[1] Hosp Galateo, Dept Rheumatol, I-73016 San Cesario Di Lecce, Italy
来源：
DRUG DESIGN DEVELOPMENT AND THERAPY | 2011年 / 5卷
关键词：
clodronate; bisphosphonates; osteoporosis; bone turnover; menopause; tolerability; BONE-MINERAL DENSITY; POSTMENOPAUSAL OSTEOPOROSIS; DOUBLE-BLIND; RISK-FACTORS; INTRAVENOUS CLODRONATE; INFLAMMATORY ACTIONS; VERTEBRAL FRACTURES; HIP FRACTURE; OPEN-LABEL; WOMEN;
D O I：
10.2147/DDDT.S12139
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Bisphosphonates have a long history in the treatment of osteoporosis and bone-related disease. This review focuses on the use of a specific nonaminobisphosphonate, clodronate, which appears to be much better tolerated than other bisphosphonates and free of high-risk contraindications. Specifically, this paper reviews its use in the prevention of osteoporosis in postmenopausal women, taking into account its tolerability profile and recent safety issues arising regarding the use of bisphosphonates.
引用
收藏
页码：445 / 454
页数：10
相关论文
共 50 条
  • [41] Osteonecrosis of the jaws in patients assuming oral bisphosphonates for osteoporosis: A retrospective multi-hospital-based study of 87 Italian cases
    Di Fede, Olga
    Fusco, Vittorio
    Matranga, Domenica
    Solazzo, Luigi
    Gabriele, Mario
    Gaeta, Giovanni M.
    Favia, Gianfranco
    Sprini, Delia
    Peluso, Franco
    Colella, Giuseppe
    Vescovi, Paolo
    Campisi, Giuseppina
    EUROPEAN JOURNAL OF INTERNAL MEDICINE, 2013, 24 (08) : 784 - 790
  • [42] Update on the utility of trabecular bone score (TBS) in clinical practice for the management of osteoporosis: a systematic review by the Egyptian Academy of Bone and Muscle Health
    El Miedany, Yasser
    Elwakil, Walaa
    Abu-Zaid, Mohammed Hassan
    Mahran, Safaa
    EGYPTIAN RHEUMATOLOGY AND REHABILITATION, 2024, 51 (01)
  • [43] Patient satisfaction and efficacy of switching from weekly bisphosphonates to monthly minodronate for treatment and prevention of glucocorticoid-induced osteoporosis in Japanese patients with systemic rheumatic diseases: a randomized, clinical trial
    Tamechika, Shin-ya
    Sasaki, Kaneshige
    Hayami, Yoshihito
    Ohmura, Shin-ichiro
    Maeda, Shinji
    Iwagaitsu, Shiho
    Naniwa, Taio
    ARCHIVES OF OSTEOPOROSIS, 2018, 13 (01)
  • [44] Overcoming barriers to secondary prevention in hip fracture patients: An electronic referral and management system for osteoporosis
    Patel, Vishal P.
    Mathew, Rajeev
    Raptis, Demitri
    Christofi, Theodoros
    Youngman, James
    INJURY-INTERNATIONAL JOURNAL OF THE CARE OF THE INJURED, 2010, 41 (12): : 1249 - 1255
  • [45] Fracture rates and economic outcomes in patients with osteoporosis prescribed risedronate gastro-resistant versus other oral bisphosphonates: a claims data analysis
    Thomasius, Friederike
    Palacios, Santiago
    Alam, Asif
    Boolell, Mitra
    Vekeman, Francis
    Gauthier, Genevieve
    OSTEOPOROSIS INTERNATIONAL, 2022, 33 (01) : 217 - 228
  • [46] Clinical practice guideline for management of osteoporosis and fracture prevention in Canada: 2023 update
    Morin, Suzanne N.
    Feldman, Sidney
    Funnell, Larry
    Giangregorio, Lora
    Kim, Sandra
    McDonald-Blumer, Heather
    Santesso, Nancy
    Ridout, Rowena
    Ward, Wendy
    Ashe, Maureen C.
    Bardai, Zahra
    Bartley, Joan
    Binkley, Neil
    Burrell, Steven
    Butt, Debra
    Cadarette, Suzanne M.
    Cheung, Angela M.
    Chilibeck, Phil
    Dunn, Sheila
    Falk, Jamie
    Frame, Heather
    Gittings, William
    Hayes, Kaleen
    Holmes, Carol
    Ioannidis, George
    Jaglal, Susan B.
    Josse, Robert
    Khan, Aliya A.
    Mcintyre, Virginia
    Nash, Lynn
    Negm, Ahmed
    Papaioannou, Alexandra
    Ponzano, Matteo
    Rodrigues, Isabel B.
    Thabane, Lehana
    Thomas, Christine A.
    Tile, Lianne
    Wark, John D.
    CANADIAN MEDICAL ASSOCIATION JOURNAL, 2023, 195 (39) : E1333 - E1348
  • [47] A Retrospective Clinical and Radiographic Study on Healing of Periradicular Lesions in Patients Taking Oral Bisphosphonates
    Hsiao, Angela
    Glickman, Gerald
    He, Jianing
    JOURNAL OF ENDODONTICS, 2009, 35 (11) : 1525 - 1528
  • [48] Patient considerations in the management of multiple sclerosis: development and clinical utility of oral agents
    Girouard, Nathalie
    Soucy, Nanda
    PATIENT PREFERENCE AND ADHERENCE, 2011, 5 : 101 - 108
  • [49] Conservative surgical treatment of medication related osteonecrosis of the jaw (MRONJ) lesions in patients affected by osteoporosis exposed to oral bisphosphonates: 24 months follow-up
    Nisi, Marco
    Karapetsa, Dimitra
    Gennai, Stefano
    Ramaglia, Luca
    Graziani, Filippo
    Gabriele, Mario
    JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY, 2018, 46 (07) : 1153 - 1158
  • [50] Clinical utility of carotid ultrasonography: Application for the management of patients with diabetes
    Katakami, Naoto
    Matsuoka, Taka-aki
    Shimomura, Iichiro
    JOURNAL OF DIABETES INVESTIGATION, 2019, 10 (04) : 883 - 898
12345