Natural Killer Cell-Based Immunotherapy in Gynecologic Malignancy: A Review

被引：42
|
作者：
Uppendahl, Locke D. [1 ]
Dahl, Carly M. [2 ]
Miller, Jeffrey S. [3 ]
Felices, Martin [3 ]
Geller, Melissa A. [1 ]
机构：
[1] Univ Minnesota, Sch Med, Div Gynecol Oncol, Dept Obstet Gynecol & Womens Hlth, Minneapolis, MN 55455 USA
[2] Univ Minnesota, Sch Med, Minneapolis, MN 55455 USA
[3] Univ Minnesota, Sch Med, Dept Med, Div Hematol Oncol & Transplantat, Minneapolis, MN 55455 USA
来源：
FRONTIERS IN IMMUNOLOGY | 2018年 / 8卷
关键词：
natural killer cells; immunotherapy; gynecologic malignancy; ovarian cancer; cervical cancer; TUMOR-INFILTRATING LYMPHOCYTES; APOPTOSIS-INDUCING LIGAND; OVARIAN-CANCER PATIENTS; CLASS-I MOLECULES; ANTI-CD20; MONOCLONAL-ANTIBODY; PERIPHERAL-BLOOD LYMPHOCYTES; IFN-GAMMA PRODUCTION; UTERINE NK CELLS; ACTIVATING RECEPTOR; ADOPTIVE TRANSFER;
D O I：
10.3389/fimmu.2017.01825
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Harnessing the immune system has proven an effective therapy in treating malignancies. Since the discovery of natural killer (NK) cells, strategies aimed to manipulate and augment their effector function against cancer have been the subject of intense research. Recent progress in the immunobiology of NK cells has led to the development of promising therapeutic approaches. In this review, we will focus on the recent advances in NK cell immunobiology and the clinical application of NK cell immunotherapy in ovarian, cervical, and uterine cancer.
引用
收藏
页数：15
相关论文
共 50 条
  • [1] Cell-based immunotherapy in gynecologic malignancies
    Kamat, Kalika
    Krishnan, Venkatesh
    Berek, Jonathan S.
    Dorigo, Oliver
    CURRENT OPINION IN OBSTETRICS & GYNECOLOGY, 2021, 33 (01) : 13 - 18
  • [2] Natural killer cell-based immunotherapy for lung cancer: Challenges and perspectives
    Zeng, Yongqin
    Lv, Xiuzhi
    Du, Juan
    ONCOLOGY REPORTS, 2021, 46 (05)
  • [3] Natural killer cell-based immunotherapy for cancer
    Ma, Shoubao
    Yu, Jianhua
    Caligiuri, Michael A.
    JOURNAL OF IMMUNOLOGY, 2025,
  • [4] Natural killer cell-based immunotherapy for acute myeloid leukemia
    Xu, Jing
    Niu, Ting
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2020, 13 (01)
  • [5] Ovarian cancer treatment and natural killer cell-based immunotherapy
    Fan, Zhongru
    Han, Dongyu
    Fan, Xin
    Zhao, Lin
    FRONTIERS IN IMMUNOLOGY, 2023, 14
  • [6] Cell-based immunotherapy in gynecologic malignancies
    Schaar, Bruce
    Krishnan, Venkatesh
    Tallapragada, Supreeti
    Chanana, Anita
    Dorigo, Oliver
    CURRENT OPINION IN OBSTETRICS & GYNECOLOGY, 2019, 31 (01) : 43 - 48
  • [7] Natural Killer Cell-Based Cancer Immunotherapy: A Review on 10 Years Completed Clinical Trials
    Suen, Wade Chun-Wai
    Lee, Wayne Yuk-Wai
    Leung, Kam-Tong
    Pan, Xiao-Hua
    Li, Gang
    CANCER INVESTIGATION, 2018, 36 (08) : 431 - 457
  • [8] Natural Killer Cell-Based Immunotherapy for Cancer: Advances and Prospects
    Hu, Yuan
    Tian, Zhigang
    Zhang, Cai
    ENGINEERING, 2019, 5 (01) : 106 - 114
  • [9] Natural killer cell-based immunotherapy for acute myeloid leukemia
    Jing Xu
    Ting Niu
    Journal of Hematology & Oncology, 13
  • [10] Cell-based immunotherapy in gynecologic malignancies
    Schaar, Bruce
    Krishnan, Venkatesh
    Tallapragada, Supreeti
    Dorigo, Oliver
    CURRENT OPINION IN OBSTETRICS & GYNECOLOGY, 2018, 30 (01) : 23 - 30
12345