Application of liquid chromatography/electrospray ionization tandem mass spectrometry to the analysis of polyphenolic compounds from an infusion of Byrsonima crassa Niedenzu

被引：33
作者：
Sannomiya, M
Montoro, P
Piacente, S
Pizza, C
Brito, ARMS
Vilegas, W
机构：
[1] Univ Estadual Paulista, Dept Organ Chem, Inst Quim, BR-14800900 Sao Paulo, Brazil
[2] Univ Salerno, Dipartimento Sci Farmaceut, I-84084 Fisciano, SA, Italy
[3] Univ Estadual Campinas, Dept Fisiol & Biofis, Inst Biol, BR-13083970 Campinas, SP, Brazil
来源：
RAPID COMMUNICATIONS IN MASS SPECTROMETRY | 2005年 / 19卷 / 16期
基金：
巴西圣保罗研究基金会;
关键词：
D O I：
10.1002/rcm.2053
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
A fast and reliable method, based on high-performance liquid chromatography coupled to electrospray ionization ion trap tandem mass spectrometry (HPLC/ESI-ITMS), was developed to investigate the infusion prepared from the leaves of Byrsonima crassa Niedenzu (Malpighiaceae), a native plant used in Brazil against gastric disorders. The use of on-line reverse-phase HPLC/ESI-ITMS allowed separation of three major classes of compounds and identification of over 20 very polar compounds characterized as galloylquinic acids, proanthocyanidins, and flavonoid glycosides, as well as the dimeric flavonoid amentoflavone and minor amounts of galloyl hexose and galloyl saccharose. This approach provided data that will allow establishment of a method for a future standardization of the infusion. Copyright (C) 2005 John Wiley & Sons, Ltd.
引用
收藏
页码：2244 / 2250
页数：7
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