An efficient one-pot method for the synthesis of novel ferrocene-triamide conjugates via pseudo five-component reaction

被引：16

作者：

Teimouri, Mohammad Bagher ^{[1
]}

Akbari-Moghaddam, Peyman ^{[1
]}

机构：

[1] Iran Polymer & Petrochem Inst, Petrochem Dept, Tehran, Iran

来源：

TETRAHEDRON | 2011年 / 67卷 / 33期

关键词：

Ferrocene-amide conjugate; Isocyanide; Meldrum's acid; Multicomponent reaction; ISOPROPYLIDENE MELDRUMS ACID; ORGANOMETALLIC ANALOG; ALKYL ISOCYANIDES; FACILE SYNTHESIS; DRUG DISCOVERY; DERIVATIVES;

D O I：

10.1016/j.tet.2011.06.048

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple and efficient one-pot synthesis of novel ferrocene-triamide conjugates from the reaction of ferrocenecarboxaldehyde with Meldrum's acid and isocyanides in the presence of NH-containing compounds is described. This transformation proceeds through the creation of two C-C bonds, two C-N bonds, and one C=O bond, leading to three peptide bonds, and presumably occurs via a domino sequence involving Knoevenagel condensation, [1+4] cycloaddition, deacetonation, and aminolysis reactions. (C) 2011 Elsevier Ltd. All rights reserved.

引用

页码：5928 / 5934

页数：7

共 50 条

[21] Synthesis of novel series of malonamides derivatives via a five-component reaction
Abbas Rahmati
Tahmineh Kenarkoohi
Mahdi Ahmadi-Varzaneh
Molecular Diversity, 2013, 17 : 619 - 625
[22] Synthesis of furan annulated heterocycles via a one-pot three-component reaction
Mosslemin, Mohammad Hossein
Anary-Abbasinejad, Mohammad
Nia, Abbas Fazli
Bakhtiari, Samaneh
Anaraki-Ardakani, Hossein
JOURNAL OF CHEMICAL RESEARCH, 2009, (10) : 599 - 601
[23] A novel one-pot pseudo-four-component isocyanide-based reaction: an unexpected approach for the synthesis of tetrahydrodiisoindoloquinoxalines and tetrahydrobenzodiisoindoloquinoxalines
Shaabani, Ahmad
Hajishaabanha, Fatemeh
Mahyari, Mojtaba
Mofakham, Hamid
Ng, Seik Weng
TETRAHEDRON, 2011, 67 (43) : 8360 - 8366
[24] Facile one-pot synthesis of novel dicyanoanilines fused to dithiane ring via a pseudo-four-component reaction
Abaee, M. Saeed
Ehteshami, Fatemeh
Forghani, Soodabeh
Mojtahedi, Mohammad M.
Hadizadeh, Atefeh
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2017, 14 (06) : 1151 - 1157
[25] One-pot five-component synthesis of highly functionalized piperidines using oxalic acid dihydrate as a homogenous catalyst
Sajadikhah, Seyed Sajad
Maghsoodlou, Malek Taher
Hazeri, Nourallah
Habibi-Khorassani, Sayyed Mostafa
Willis, Anthony C.
CHINESE CHEMICAL LETTERS, 2012, 23 (05) : 569 - 572
[26] Iodine catalyzed one-pot five-component reactions for direct synthesis of densely functionalized piperidines
Khan, Abu T.
Khan, Md. Musawwer
Bannuru, Kranthi K. R.
TETRAHEDRON, 2010, 66 (39) : 7762 - 7772
[27] An efficient and ecofriendly synthesis of highly functionalized pyridones via a one-pot three-component reaction
Hosseini, Hajar
Bayat, Mohammad
RSC ADVANCES, 2018, 8 (48) : 27131 - 27143
[28] A Simple One-Pot Procedure for the Synthesis of 1,2,4-Triazolo[1,5-a]pyridines via Pseudo Five-Component Reactions Catalyzed by Molecular Iodine
Alizadeh, Abdolali
Saberi, Vahid
Mokhtari, Javad
SYNLETT, 2013, 24 (14) : 1825 - 1829
[29] Sequential one-pot five-component synthesis of tetrazole-based spirotetrahydro-β-carbolines
Ghandi, Mehdi
Ahangaran, Mahdieh Mahami
Abbasi, Alireza
JOURNAL OF THE IRANIAN CHEMICAL SOCIETY, 2017, 14 (05) : 1131 - 1137
[30] FACILE AND HIGHLY EFFICIENT PROCEDURE FOR THE SYNTHESIS OF TRIAZOLYL METHOXYPHENYL 1,8-DIOXO-DECAHYDROACRIDINES VIA ONE-POT, PSEUDO-FIVE-COMPONENT REACTION
Dabiri, Minoo
Salehi, Peyman
Bahramnejad, Mahboobeh
Sherafat, Fatemeh
Bararjanian, Morteza
SYNTHETIC COMMUNICATIONS, 2012, 42 (21) : 3117 - 3127

← 1 2 3 4 5 →