A practical and efficient synthesis of chiral N,N-disubstituted C2 symmetric diamines derived from (R,R)-1,2-diaminocyclohexane

被引：30

作者：

Alexakis, A ^{[1
]}

Chauvin, AS ^{[1
]}

Stouvenel, R ^{[1
]}

Vrancken, E ^{[1
]}

Mutti, S ^{[1
]}

Mangeney, P ^{[1
]}

机构：

[1] Univ Geneva, Dept Organ Chem, CH-1211 Geneva 4, Switzerland

来源：

TETRAHEDRON-ASYMMETRY | 2001年 / 12卷 / 08期

关键词：

D O I：

10.1016/S0957-4166(01)00198-7

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An improved synthesis of chiral diamine ligands derived from (R,R)-1,2-diaminocyclohexane is described, providing N-substituted diamines. The synthesis of other neu ligands based on this methodology, is also reported. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：1171 / 1178

页数：8

共 21 条

[1] ENANTIOSELECTIVE ORTHO-LITHIATION OF BENZALDEHYDE CHROMIUMTRICARBONYL COMPLEX [J].

ALEXAKIS, A ;

KANGER, T ;

MANGENEY, P ;

ROSEMUNCH, F ;

PERROTEY, A ;

ROSE, E .

TETRAHEDRON-ASYMMETRY, 1995, 6 (09) :2135-2138

[2] A NEW REAGENT FOR THE DETERMINATION OF THE OPTICAL PURITY OF PRIMARY, SECONDARY, AND TERTIARY CHIRAL ALCOHOLS AND OF THIOLS [J].

ALEXAKIS, A ;

MUTTI, S ;

MANGENEY, P .

JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (04) :1224-1237

[3]

Alexakis A., 1996, ADV ASYMMETRIC SYNTH, P93

[4]

ALEXAKIS A, UNPUB

[5] trans-1,2-diaminocyclohexane derivatives as chiral reagents, scaffolds, and ligands for catalysis: Applications in asymmetric synthesis and molecular recognition [J].

Bennani, YL ;

Hanessian, S .

CHEMICAL REVIEWS, 1997, 97 (08) :3161-3195

[6] The asymmetric synthesis of alpha-substituted alpha-methyl and alpha-phenyl phosphonic acids: Design, carbanion geometry, reactivity and preparative aspects of chiral alkyl bicyclic phosphonamides [J].

Bennani, YL ;

Hanessian, S .

TETRAHEDRON, 1996, 52 (44) :13837-13866

[7]

BENNANI YL, 1998, ANGEW CHEM INT EDIT, V37, P2580

[8] CARBANION-ACCELERATED CLAISEN REARRANGEMENTS .8. PHOSPHONAMIDE ANION-STABILIZING GROUPS [J].

DENMARK, SE ;

STADLER, H ;

DOROW, RL ;

KIM, JH .

JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (17) :5063-5079

[9] Structure of the copper(II) complex of the reinforced ligand N,N'-bis(trans-2-hydroxycyclohexyl)-trans-cyclohexane-1,2-diamine and the metal-ion-size-based selectivity produced by cyclohexanediyl bridges [J].

DeSousa, AS ;

Hancock, RD ;

Reibenspies, JH .

JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1997, (16) :2831-2835

[10] CONVENIENT SYNTHESES, BASED ON CYCLOHEXENE OXIDE, OF LIGANDS THAT ARE HIGHLY PREORGANISED FOR METAL-ION SIZE-BASED SELECTIVITY [J].

DESOUSA, AS ;

HANCOCK, RD .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1995, (04) :415-416

← 1 2 3 →