Possible mechanisms by which alcohol may influence the development of oral cancer - a review

被引:99
作者
Wight, AJ [1 ]
Ogden, GR [1 ]
机构
[1] Univ Dundee, Dundee Dent Hosp & Sch, Unit Oral Med & Oral Surg, Dundee, Scotland
关键词
alcohol; tobacco; oral cancer; oral mucosa;
D O I
10.1016/S1368-8375(98)00022-0
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Although pure ethanol has never been shown to be carcinogenic in laboratory experiments, alcoholic beverages are now recognised as being important aetiological factors in the development of oral cancer. Despite this, the exact mechanism by which alcohol may exert an influence upon the oral mucosa has received less attention. An overview of the association of alcohol and oral cancer, both in combination with tobacco and without, is provided and consideration given to some of the pathways by which alcohol exerts its effect upon the oral mucosa. (C) 1998 Elsevier Science Ltd. All rights reserved.
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页码:441 / 447
页数:7
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