Synthesis of macrocyclic scaffolds from natural products and their utilization for solid-phase chemistry

被引：5
|
作者：
Grosche, P
Akyel, KG
Marzinzik, AL [1 ]
机构：
[1] Novartis Inst BioMed Res, Global Discovery Chem, Lead Synth & Chemogenet, CH-4002 Basel, Switzerland
[2] Novartis Inst BioMed Res, Discovery Technol, Analyt & Imaging Sci, CH-4002 Basel, Switzerland
来源：
SYNTHESIS-STUTTGART | 2005年 / 12期
关键词：
combinatorial chemistry; natural products; solid-phase synthesis;
D O I：
10.1055/s-2005-869969
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The versatile synthesis of natural product derived macrocyclic scaffolds suitable for solid- and for solution-phase chemistry is shown. The scaffolds are modified by solid-phase chemistry to yield macrocycles with two points of diversity.
引用
收藏
页码：2015 / 2021
页数：7
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