High risk HPV testing following treatment for cervical intraepithelial neoplasia

被引：5

作者：

Molloy, M. ^{[1
]}

Comer, R. ^{[1
]}

Rogers, P. ^{[1
]}

Dowling, M. ^{[2
]}

Meskell, P. ^{[2
]}

Asbury, K. ^{[1
]}

O'Leary, M. ^{[1
]}

机构：

[1] Univ Hosp, Womens & Childrens Directorate, Newcastle Rd, Galway, Ireland

[2] Natl Univ Ireland, Sch Nursing & Midwifery, Univ Rd, Galway, Ireland

来源：

IRISH JOURNAL OF MEDICAL SCIENCE | 2016年 / 185卷 / 04期

关键词：

Audit; Cervical intraepithelial neoplasia; Colposcopy; HPV DNA tests; Papanicolaou test; LOOP EXCISION; PREVENTION; PREDICTION; DISEASE;

D O I：

10.1007/s11845-015-1392-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To determine the results of combined cytology and high-risk human papilloma virus (HR HPV) tests at 6 and 18 months postcolposcopy treatment at one Irish colposcopy centre. All women who attended the centre's colposcopy smear clinic for a co-test 6 months (initial test) posttreatment were included in the audit (n = 251). The results revealed negative HR HPV for 79 % (n = 198) of women tested 6 months after treatment and positive results for 21 % (n = 53). HR HPV testing was more sensitive than cytology and led to early detection of residual disease. No women with negative HR HPV had high-grade cytology. HR HPV is more sensitive than cytology for detection of persistent CIN. However, 19 women with positive HR HPV had normal colposcopy with no persistent CIN detected. A national cost-benefit analysis is recommended to determine the value of the second co-test.

引用

页码：895 / 900

页数：6

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