STABLE EXPRESSION AND POTENTIAL USE OF WEST NILE VIRUS ENVELOPE GLYCOPROTEINS preM/E AS ANTIGEN IN DIAGNOSTIC TESTS

被引：0

作者：

Cargnelutti, Juliana Felipetto ^{[1
]}

Sperotto Brum, Mario Celso ^{[2
]}

Weiblen, Rudi ^{[1
]}

Flores, Eduardo Furtado ^{[1
]}

机构：

[1] Univ Fed Santa Maria, Dept Vet Prevent Med, Setor Virol, Ctr Ciencias Rurais, BR-97105900 Santa Maria, RS, Brazil

[2] Univ Fed Pampa, Fac Med Vet, Uruguaiana, RS, Brazil

来源：

BRAZILIAN JOURNAL OF MICROBIOLOGY | 2011年 / 42卷 / 03期

关键词：

West Nile virus; WNV; M/E glycoproteins; stable expression; diagnostic; INFECTION; ARGENTINA; DISEASE; HORSES;

D O I：

暂无

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

West Nile virus (WNV) envelope glycoproteins preM/E were stably expressed in baby hamster kidney cells and tested as antigen in a fluorescent antibody assay for WNV antibodies. Sera from horses, mice and chicken immunized with an inactivated WNV vaccine and, less consistently, sera from horses acutely infected with WNV, reacted specifically with viral antigens present in preM/E-expressing cells.

引用

页码：1160 / 1165

页数：6

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