Complexation of antibiotic levomycetin (Chloroamphenicol) with α-hederin and hederasaponin c under the conditions of electrospray ionization

被引：1

作者：

Lekar', A. V. ^{[1
]}

Yakovishin, L. A. ^{[2
]}

Borisenko, S. N. ^{[1
]}

Vetrova, E. V. ^{[1
]}

Borisenko, N. I. ^{[3
]}

机构：

[1] So Fed Univ, Res Inst Phys & Organ Chem, Rostov Na Donu 344090, Russia

[2] Sevastopol Natl Tech Univ, Chair Phys, Course Chem, UA-99053 Sevastopol, Ukraine

[3] So Fed Univ, Ctr Analyt & Ecol, Rostov Na Donu 344090, Russia

来源：

JOURNAL OF ANALYTICAL CHEMISTRY | 2011年 / 66卷 / 14期

关键词：

electrospray ionization mass spectrometry; triterpene glycoside; alpha-hederin; hederasaponin C; levomycetin; molecular complex; TRITERPENE GLYCOSIDES;

D O I：

10.1134/S1061934811140115

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The complexation of antibiotic levomycetin (chloroamphenicol) with triterpene glycoside alpha-hederin and hederasaponin C was investigated by electrospray ionization mass spectrometry. The glycosides form complexes with levomycetin in the molar ratio 1: 1. The molecular complex of alpha-hederin is more stable than the one of hederasaponin C because of the presence of a free carboxyl group in its aglycone fragment. The carboxyl group of hederasaponin C is involved into the formation of a glycosidic bond with the trisaccharide unit and is not available for complex formation.

引用

页码：1437 / 1440

页数：4

共 4 条

[1] Complexation of antibiotic levomycetin (Chloroamphenicol) with α-hederin and hederasaponin c under the conditions of electrospray ionization
A. V. Lekar’
L. A. Yakovishin
S. N. Borisenko
E. V. Vetrova
N. I. Borisenko
Journal of Analytical Chemistry, 2011, 66 : 1437 - 1440
[2] Molecular complexation of α-hederin with hederasaponin C
Yakovishin, L. A.
Grishkovets, V. I.
Lekar, A. B.
Vetrova, E. V.
Borisenko, N. I.
Borisenko, S. N.
RUSSIAN JOURNAL OF BIOORGANIC CHEMISTRY, 2013, 39 (07) : 707 - 711
[3] Molecular complexation of α-hederin with hederasaponin C
L. A. Yakovishin
V. I. Grishkovets
A. B. Lekar
E. V. Vetrova
N. I. Borisenko
S. N. Borisenko
Russian Journal of Bioorganic Chemistry, 2013, 39 : 707 - 711
[4] Enantiomeric differentiation of β-amino alcohols under electrospray ionization mass spectrometric conditions
Karthikraj, R.
Chitumalla, Ramesh Kumar
Bhanuprakash, Kotamarthi
Prabhakar, S.
Vairamani, M.
JOURNAL OF MASS SPECTROMETRY, 2014, 49 (01): : 108 - 116

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