Renal insufficiency is associated with increased morbidity and death after endovascular aortic aneurysm repair (EVAR). However, the effect of postoperative acute kidney dysfunction on patient outcome has not been fully determined. This study aimed to determine the risk factors of early postoperative renal function decline using chronic kidney disease (CKD) staging and its effect on the clinical outcome. A retrospective analysis was performed on a prospectively maintained EVAR database. Pre- and postoperative CKD stages were determined for all patients according to the estimated glomerular filtration rate values. We identified 135 patients who were treated with elective EVAR. CKD stage decline was observed in 25 (19 %) of the patients. Freedom from aneurysm-related death was significantly lower in patients with postoperative CKD progression compared with those with unchanged CKD stage. A shaggy aorta without oral beta-blocker administration and higher preoperative serum creatinine levels (> 1.4 mg/dL) were found to be independent predictors of an early postoperative CKD stage decline. Patients with postoperative CKD progression have an increased frequency of aneurysm-related death. The presence of a shaggy aorta, absence of oral beta-blocker administration and an increased preoperative creatinine level are independent predictors of early postoperative CKD progression.
机构:
Univ Manchester, Univ S Manchester Hosp, Manchester Acad Hlth Sci Ctr, Acad Surg Unit,Educ & Res Ctr, Manchester M23 9LT, Lancs, EnglandUniv Manchester, Univ S Manchester Hosp, Manchester Acad Hlth Sci Ctr, Acad Surg Unit,Educ & Res Ctr, Manchester M23 9LT, Lancs, England
Grant, S. W.
Grayson, A. D.
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Liverpool Heart & Chest Hosp NHS Fdn Trust, Liverpool L14 3PE, Merseyside, EnglandUniv Manchester, Univ S Manchester Hosp, Manchester Acad Hlth Sci Ctr, Acad Surg Unit,Educ & Res Ctr, Manchester M23 9LT, Lancs, England
Grayson, A. D.
Grant, M. J.
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机构:Univ Manchester, Univ S Manchester Hosp, Manchester Acad Hlth Sci Ctr, Acad Surg Unit,Educ & Res Ctr, Manchester M23 9LT, Lancs, England
Grant, M. J.
Purkayastha, D.
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机构:Univ Manchester, Univ S Manchester Hosp, Manchester Acad Hlth Sci Ctr, Acad Surg Unit,Educ & Res Ctr, Manchester M23 9LT, Lancs, England
Purkayastha, D.
McCollum, C. N.
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Univ Manchester, Univ S Manchester Hosp, Manchester Acad Hlth Sci Ctr, Acad Surg Unit,Educ & Res Ctr, Manchester M23 9LT, Lancs, EnglandUniv Manchester, Univ S Manchester Hosp, Manchester Acad Hlth Sci Ctr, Acad Surg Unit,Educ & Res Ctr, Manchester M23 9LT, Lancs, England
机构:
Sichuan Univ, West China Med Sch, Chengdu 610041, Sichuan, Peoples R ChinaSichuan Univ, West China Med Sch, Chengdu 610041, Sichuan, Peoples R China
Wu, Zuowei
Yuan, Ding
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West China Hosp, Dept Vasc Surg, Chengdu 610041, Sichuan, Peoples R ChinaSichuan Univ, West China Med Sch, Chengdu 610041, Sichuan, Peoples R China
Yuan, Ding
Zhao, Jichun
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West China Hosp, Dept Vasc Surg, Chengdu 610041, Sichuan, Peoples R ChinaSichuan Univ, West China Med Sch, Chengdu 610041, Sichuan, Peoples R China
Zhao, Jichun
Huang, Bin
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West China Hosp, Dept Vasc Surg, Chengdu 610041, Sichuan, Peoples R ChinaSichuan Univ, West China Med Sch, Chengdu 610041, Sichuan, Peoples R China
机构:
St George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, EnglandSt George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, England
Karthikesalingam, Alan
Bahia, Sandeep S.
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St George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, EnglandSt George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, England
Bahia, Sandeep S.
Patel, Shaneel R.
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St George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, EnglandSt George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, England
Patel, Shaneel R.
Azhar, Bilal
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St George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, EnglandSt George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, England
Azhar, Bilal
Jackson, Dan
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Univ Cambridge, Inst Publ Hlth, MRC Biostat Unit, Cambridge, EnglandSt George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, England
Jackson, Dan
Cresswell, Lynne
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Univ Cambridge, Inst Publ Hlth, MRC Biostat Unit, Cambridge, EnglandSt George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, England
Cresswell, Lynne
Hinchliffe, Robert J.
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St George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, EnglandSt George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, England
Hinchliffe, Robert J.
Holt, Peter J. E.
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St George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, EnglandSt George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, England
Holt, Peter J. E.
Thompson, Matt M.
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St George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, EnglandSt George Hosp, NHS Trust, St Georges Vasc Inst, Dept Outcomes Res, 4th Floor,St James Wing, London SW17 0QT, England
机构:
Baylor Coll Med, Div Vasc Surg & Endovasc Therapy, Houston, TX 77030 USA
Baylor Coll Med, Michael E DeBakey Dept Surg, Houston, TX 77030 USABaylor Coll Med, Div Vasc Surg & Endovasc Therapy, Houston, TX 77030 USA
Mohammed, Somala
Kougias, Panagiotis
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Baylor Coll Med, Div Vasc Surg & Endovasc Therapy, Houston, TX 77030 USA
Baylor Coll Med, Michael E DeBakey Dept Surg, Houston, TX 77030 USA
Michael E DeBakey VA Med Ctr, Div Vasc Surg & Endovasc Therapy, Houston, TX USABaylor Coll Med, Div Vasc Surg & Endovasc Therapy, Houston, TX 77030 USA
Kougias, Panagiotis
Mandviwala, Taher M.
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Baylor Coll Med, Div Vasc Surg & Endovasc Therapy, Houston, TX 77030 USA
Baylor Coll Med, Michael E DeBakey Dept Surg, Houston, TX 77030 USABaylor Coll Med, Div Vasc Surg & Endovasc Therapy, Houston, TX 77030 USA
Mandviwala, Taher M.
Barshes, Neal R.
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Baylor Coll Med, Div Vasc Surg & Endovasc Therapy, Houston, TX 77030 USA
Baylor Coll Med, Michael E DeBakey Dept Surg, Houston, TX 77030 USA
Michael E DeBakey VA Med Ctr, Div Vasc Surg & Endovasc Therapy, Houston, TX USABaylor Coll Med, Div Vasc Surg & Endovasc Therapy, Houston, TX 77030 USA
Barshes, Neal R.
Pisimisis, George T.
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Baylor Coll Med, Div Vasc Surg & Endovasc Therapy, Houston, TX 77030 USA
Baylor Coll Med, Michael E DeBakey Dept Surg, Houston, TX 77030 USA
Michael E DeBakey VA Med Ctr, Div Vasc Surg & Endovasc Therapy, Houston, TX USABaylor Coll Med, Div Vasc Surg & Endovasc Therapy, Houston, TX 77030 USA