Evaluation of cycle threshold values at deisolation

被引：14
作者：
Mowrer, Clayton T. [1 ]
Creager, Hannah [2 ]
Cawcutt, Kelly [1 ]
Birge, Justin [3 ]
Lyden, Elizabeth [4 ]
Van Schooneveld, Trevor C. [1 ]
Rupp, Mark E. [1 ]
Hewlett, Angela [1 ]
机构：
[1] Univ Nebraska Med Ctr, Div Infect Dis, Omaha, NE 68198 USA
[2] Univ Nebraska Med Ctr, Dept Pathol & Microbiol, Omaha, NE USA
[3] Univ Nebraska Med Ctr, Dept Internal Med, Omaha, NE USA
[4] Univ Nebraska Med Ctr, Coll Publ Hlth, Omaha, NE USA
来源：
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY | 2022年 / 43卷 / 06期
关键词：
D O I：
10.1017/ice.2021.132
中图分类号：
R1 [预防医学、卫生学];
学科分类号：
1004 ; 120402 ;
摘要：
The decision to discontinue isolation in hospitalized patients with persistently positive severe acute respiratory coronavirus virus 2 (SARS-CoV-2) molecular testing is nuanced. Improvement in clinical status should be evaluated with expert consultation when considering whether discontinuation of isolation is appropriate. The cycle threshold value may serve as a useful adjunct to this decision-making process.
引用
收藏
页码：794 / 796
页数：3
相关论文
共 10 条
  • [1] [Anonymous], CLIN SPECTRUM SARS C
  • [2] Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host
    Choi, Bina
    Choudhary, Manish C.
    Regan, James
    Sparks, Jeffrey A.
    Padera, Robert F.
    Qiu, Xueting
    Solomon, Isaac H.
    Kuo, Hsiao-Hsuan
    Boucau, Julie
    Bowman, Kathryn
    Das Adhikari, U.
    Winkler, Marisa L.
    Mueller, Alisa A.
    Hsu, Tiffany Y. -T.
    Desjardins, Michael
    Baden, Lindsey R.
    Chan, Brian T.
    Walker, Bruce D.
    Lichterfeld, Mathias
    Brigl, Manfred
    Kwon, Douglas S.
    Kanjilal, Sanjat
    Richardson, Eugene T.
    Jonsson, A. Helena
    Alter, Galit
    Barczak, Amy K.
    Hanage, William P.
    Yu, Xu G.
    Gaiha, Gaurav D.
    Seaman, Michael S.
    Cernadas, Manuela
    Li, Jonathan Z.
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (23) : 2291 - 2293
  • [3] Temporal dynamics in viral shedding and transmissibility of COVID-19
    He, Xi
    Lau, Eric H. Y.
    Wu, Peng
    Deng, Xilong
    Wang, Jian
    Hao, Xinxin
    Lau, Yiu Chung
    Wong, Jessica Y.
    Guan, Yujuan
    Tan, Xinghua
    Mo, Xiaoneng
    Chen, Yanqing
    Liao, Baolin
    Chen, Weilie
    Hu, Fengyu
    Zhang, Qing
    Zhong, Mingqiu
    Wu, Yanrong
    Zhao, Lingzhai
    Zhang, Fuchun
    Cowling, Benjamin J.
    Li, Fang
    Leung, Gabriel M.
    [J]. NATURE MEDICINE, 2020, 26 (05) : 672 - 675
  • [4] SARS-CoV-2 Virus Culture and Subgenomic RNA for Respiratory Specimens from Patients with Mild Coronavirus Disease
    Perera, Ranawaka A. P. M.
    Tso, Eugene
    Tsang, Owen T. Y.
    Tsang, Dominic N. C.
    Fung, Kitty
    Leung, Yonna W. Y.
    Chin, Alex W. H.
    Chu, Daniel K. W.
    Cheng, Samuel M. S.
    Poon, Leo L. M.
    Chuang, Vivien W. M.
    Peiris, Malik
    [J]. EMERGING INFECTIOUS DISEASES, 2020, 26 (11) : 2701 - 2704
  • [5] A Narrative Systematic Review of the Clinical Utility of Cycle Threshold Values in the Context of COVID-19
    Rao, Sonia N.
    Manissero, Davide
    Steele, Victoria R.
    Pareja, Josep
    [J]. INFECTIOUS DISEASES AND THERAPY, 2020, 9 (03) : 573 - 586
  • [6] Duration of infectiousness and correlation with RT-PCR cycle threshold values in cases of COVID-19, England, January to May 2020
    Singanayagam, Anika
    Patel, Monika
    Charlett, Andre
    Bernal, Jamie Lopez
    Saliba, Vanessa
    Ellis, Joanna
    Ladhani, Shamez
    Zambon, Maria
    Gopal, Robin
    [J]. EUROSURVEILLANCE, 2020, 25 (32) : 2 - 6
  • [7] Wolf RC, 2020, NEUROPSYCHOBIOLOGY, V79, P335, DOI [10.1159/000505601, 10.1038/s41586-020-2984-3]
  • [8] Factors Associated With Prolonged Viral RNA Shedding in Patients with Coronavirus Disease 2019 (COVID-19)
    Xu, Kaijin
    Chen, Yanfei
    Yuan, Jing
    Yi, Ping
    Ding, Cheng
    Wu, Wenrui
    Li, Yongtao
    Ni, Qin
    Zou, Rongrong
    Li, Xiaohe
    Xu, Min
    Zhang, Ying
    Zhao, Hong
    Zhang, Xuan
    Yu, Liang
    Su, Junwei
    Lang, Guanjing
    Liu, Jun
    Wu, Xiaoxin
    Guo, Yongzheng
    Tao, Jingjing
    Shi, Ding
    Yu, Ling
    Cao, Qing
    Ruan, Bing
    Liu, Lei
    Wang, Zhaoqin
    Xu, Yan
    Liu, Yingxia
    Sheng, Jifang
    Li, Lanjuan
    [J]. CLINICAL INFECTIOUS DISEASES, 2020, 71 (15) : 799 - 806
  • [9] Viral Dynamics and Immune Correlates of Coronavirus Disease 2019 (COVID-19) Severity
    Young, Barnaby E.
    Ong, Sean W. X.
    Ng, Lisa F. P.
    Anderson, Danielle E.
    Chia, Wan Ni
    Chia, Po Ying
    Ang, Li Wei
    Mak, Tze-Minn
    Kalimuddin, Shirin
    Chai, Louis Yi Ann
    Pada, Surinder
    Tan, Seow Yen
    Sun, Louisa
    Parthasarathy, Purnima
    Fong, Siew-Wai
    Chan, Yi-Hao
    Tan, Chee Wah
    Lee, Bernett
    Rotzschke, Olaf
    Ding, Ying
    Tambyah, Paul
    Low, Jenny G. H.
    Cui, Lin
    Barkham, Timothy
    Lin, Raymond Tzer Pin
    Leo, Yee-Sin
    Renia, Laurent
    Wang, Lin-Fa
    Lye, David Chien
    [J]. CLINICAL INFECTIOUS DISEASES, 2021, 73 (09) : E2932 - E2942
  • [10] Viral load dynamics and disease severity in patients infected with SARS-CoV-2 in Zhejiang province, China, January-March 2020: retrospective cohort study
    Zheng, Shufa
    Fan, Jian
    Yu, Fei
    Feng, Baihuan
    Lou, Bin
    Zou, Qianda
    Xie, Guoliang
    Lin, Sha
    Wang, Ruonan
    Yang, Xianzhi
    Chen, Weizhen
    Wang, Qi
    Zhang, Dan
    Liu, Yanchao
    Gong, Renjie
    Ma, Zhaohui
    Lu, Siming
    Xiao, Yanyan
    Gu, Yaxi
    Zhang, Jinming
    Yao, Hangping
    Xu, Kaijin
    Lu, Xiaoyang
    Wei, Guoqing
    Zhou, Jianying
    Fang, Qiang
    Cai, Hongliu
    Qiu, Yunqing
    Sheng, Jifang
    Chen, Yu
    Liang, Tingbo
    [J]. BMJ-BRITISH MEDICAL JOURNAL, 2020, 369
1