Review of research on quantitative structure-retention relationships in thin-layer chromatography

被引：71

作者：

Wang, QS ^{[1
]}

Zhang, L ^{[1
]}

机构：

[1] Nankai Univ, Natl Lab Elementoorgan Chem, Tianjin 300071, Peoples R China

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY & RELATED TECHNOLOGIES | 1999年 / 22卷 / 01期

关键词：

D O I：

10.1081/JLC-100101639

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A review is given on the quantitative structure-retention relationship (QSRR) in TLC. The establishment of QSRR equations is described, which is based on physico-chemical parameters, non-specific parameters, topological indices, and a combination of physico-chemical parameters. The application of QSRR for prediction of retention, determination of lipophilicity, evaluation of some physico-chemical parameters of chemicals, evaluation of biological activity of compounds, and explanation of separation mechanisms are also reviewed.

引用

页码：1 / 14

页数：14

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