Latest Trends in Surface Modification for Dental Implantology: Innovative Developments and Analytical Applications

被引：63

作者：

Accioni, Francesca ^{[1
]}

Vazquez, Juan ^{[2
]}

Merinero, Manuel ^{[1
,3
]}

Begines, Belen ^{[1
]}

Alcudia, Ana ^{[1
]}

机构：

[1] Univ Seville, Dept Quim Organ & Farmaceut, Seville 41012, Spain

[2] Univ Seville, Dept Quim Organ, Seville 41012, Spain

[3] Univ Seville, Dept Citol & Histol Normal & Patol, Seville 41012, Spain

来源：

PHARMACEUTICS | 2022年 / 14卷 / 02期

关键词：

dental implants; osseointegration; antimicrobial activity; inorganic coatings; polymeric coatings; nanotechnology; drug delivery; biomedical applications; pharmaceutical agents; biomaterials; DRUG-DELIVERY SYSTEMS; IN-VITRO; ANTIMICROBIAL ACTIVITY; GRAPHENE OXIDE; SILVER NANOPARTICLES; MASS-SPECTROMETRY; BIOACTIVE GLASS; ANTIBACTERIAL PROPERTIES; CARBOXYMETHYL CHITOSAN; NANOCOMPOSITE COATINGS;

D O I：

10.3390/pharmaceutics14020455

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

An increase in the world population and its life expectancy, as well as the ongoing concern about our physical appearance, have elevated the relevance of dental implantology in recent decades. Engineering strategies to improve the survival rate of dental implants have been widely investigated, focusing on implant material composition, geometry (usually guided to reduce stiffness), and interface surrounding tissues. Although efforts to develop different implant surface modifications are being applied in commercial dental prostheses today, the inclusion of surface coatings has gained special interest, as they can be tailored to efficiently enhance osseointegration, as well as to reduce bacterial-related infection, minimizing peri-implantitis appearance and its associated risks. The use of biomaterials to replace teeth has highlighted the need for the development of reliable analytical methods to assess the therapeutic benefits of implants. This literature review considers the state-of-the-art strategies for surface modification or coating and analytical methodologies for increasing the survival rate for teeth restoration.

引用

页数：38

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