Chloride transport in the ferret trachea

被引：4
|
作者：
Gerencser, GA
Loughlin, GM
Crowder, MA
机构：
[1] Univ Florida, Coll Med, Dept Physiol, Gainesville, FL 32610 USA
[2] Johns Hopkins Univ, Sch Med, Dept Pediat, Pediat Pulm Div, Baltimore, MD 21205 USA
来源：
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A-MOLECULAR AND INTEGRATIVE PHYSIOLOGY | 1999年 / 122卷 / 01期
关键词：
chloride secretion; transport inhibitors; Mustela putorius furo; epithelium; trachea;
D O I：
10.1016/S1095-6433(98)10142-3
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A net secretion of chloride stimulated by carbamylcholine was observed in whole trachea. Luminal anthracene-9-carboxylic acid inhibited the net secretion of chloride and the transepithelial potential difference across the isolated trachea. Submucosal ouabain inhibited the net secretion of chloride and submucosal ouabain, or submucosal bumetanide inhibited the transepithelial potential difference across the isolated trachea. Short-circuited flat sheets of trachea manifested a net secretion of chloride induced by carbamylcholine. Serosal ouabain inhibited the short-circuit current and net chloride flux across isolated flat sheets of trachea. (C) 1999 Elsevier Science Inc. All rights reserved.
引用
收藏
页码：93 / 97
页数：5
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