Heterotopic Pregnancy with Intrauterine Partial Hydatidiform Mole and a Tubal Ectopic A Case Report

BACKGROUND: The co-occurrence of a spontaneous heterotopic pregnancy involving a partial hydatidiform mole is exceptionally rare and poses unique diagnostic challenges. CASE: A 33-year-old woman underwent a suction dilation and curettage for evacuation of a spontaneously conceived partial molar pregnancy. She presented with pelvic pain and rising human chorionic gonadotropin (hCG) levels 7 weeks later. A right ampullary ectopic pregnancy was discovered and treated by laparoscopic salpingostomy, with progressive decline of her hCG levels. CONCLUSION: This case is presented not only for the rarity of the co-occurrence of a heterotopic intrauterine partial molar and tubal ectopic pregnancy, but also as a reminder to consider the possibility of this entity with rising hCG levels following evacuation of a molar pregnancy prior to initiating treatment for persistent gestational trophoblastic disease.