Long term treatment with clarithromycin for cryptosporidiosis and emergence of drug resistant disseminated infection due to Mycobacterium avium:: Case report

被引：2

作者：

Matteelli, A ^{[1
]}

Signorini, L ^{[1
]}

Tebaldi, A ^{[1
]}

Bombana, E ^{[1
]}

Chatel, G ^{[1
]}

Pinsi, G ^{[1
]}

机构：

[1] Univ Brescia, Clin Infect & Trop Dis, I-25125 Brescia, Italy

来源：

JOURNAL OF CHEMOTHERAPY | 1998年 / 10卷 / 06期

关键词：

cryptosporidiosis; macrolides; clarithromycin; Mycobacterium avium; AIDS;

D O I：

10.1179/joc.1998.10.6.474

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Macrolide resistance in disseminated Mycobacterium avium infection is of major concern in AIDS patients as these drugs represent the main component of combination therapy. Clarithromycin and azithromycin should not be used alone for the treatment and prophylaxis of the disease because of the risk of selecting resistant strains. We report the case of a clarithromycin resistant disseminated M, avium infection in an AIDS patient, acquired after long term monotherapy with clarithromycin for the treatment of cryptosporidiosis.

引用

页码：474 / 475

页数：2

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