Transition metal- and solvent-free double hydroboration of nitriles

被引：43

作者：

Bedi, Deepika ^{[1
]}

Brar, Aneelman ^{[1
]}

Findlater, Michael ^{[1
]}

机构：

[1] Texas Tech Univ, Dept Chem & Biochem, Lubbock, TX 79423 USA

来源：

GREEN CHEMISTRY | 2020年 / 22卷 / 04期

基金：

美国国家科学基金会;

关键词：

REDUCTIVE AMINATION; CATALYZED HYDROBORATION; PRIMARY AMINES; N-ALKYLATION; COMPLEXES; ALDEHYDES; KETONES; ALCOHOLS; SINGLE;

D O I：

10.1039/c9gc04260a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A highly efficient, room temperature double hydroboration of nitriles under transition metal-free and solvent-free conditions is reported. Sodium triethylborohydride is used as a catalyst and yields up to 99% are disclosed. Mechanistic studies reveal the reaction proceeds in a stepwise manner with initial formation of a boryl-imine which undergoes a second hydroboration to afford a diborylated amine product.

引用

页码：1125 / 1128

页数：4

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