Rationalising the effect of reducing agent on the oxazaborolidine-mediated asymmetric reduction of N-substituted imines

被引：14
作者：
Kirton, EHM
Tughan, G
Morris, RE
Field, RA [1 ]
机构：
[1] Univ E Anglia, Sch Chem Sci & Pharm, Norwich NR4 7TJ, Norfolk, England
[2] Univ St Andrews, Sch Chem, St Andrews KY16 9ST, Fife, Scotland
[3] GlaxoSmithKline, Med Res Ctr, Stevenage SG2 1NE, Herts, England
来源：
TETRAHEDRON LETTERS | 2004年 / 45卷 / 04期
基金：
英国工程与自然科学研究理事会;
关键词：
D O I：
10.1016/j.tetlet.2003.11.021
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Comparing the effect of borane-based reducing agents on the stereochemical outcome of oxazaborolidine-mediated ketone and N-substituted imine reduction highlights the potential importance of reducing agent structure on the asymmetric sense of imine reduction. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：853 / 855
页数：3
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