Stem cells from adipose tissue

被引：67

作者：

Witkowska-Zimny, Malgorzata ^{[1
]}

Walenko, Katarzyna ^{[1
]}

机构：

[1] Med Univ Warsaw, Dept Biophys & Human Physiol, PL-02004 Warsaw, Poland

来源：

CELLULAR & MOLECULAR BIOLOGY LETTERS | 2011年 / 16卷 / 02期

关键词：

Adult stem cells; Adipose-derived stem cells/stromal cells; Adipose tissue; Regenerative medicine; HUMAN BONE-MARROW; STROMAL-VASCULAR FRACTION; CHONDROGENIC DIFFERENTIATION; IN-VITRO; OSTEOGENIC DIFFERENTIATION; EPITHELIAL DIFFERENTIATION; DYSTROPHIN EXPRESSION; ENDOTHELIAL-CELLS; PERFUSION CULTURE; LINEAGE CELLS;

D O I：

10.2478/s11658-011-0005-0

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

This is a review of the growing scientific interest in the developmental plasticity and therapeutic potential of stromal cells isolated from adipose tissue. Adipose-derived stem/stromal cells (ASCs) are multipotent somatic stem cells that are abundant in fat tissue. It has been shown that ASCs can differentiate into several lineages, including adipose cells, chondrocytes, osteoblasts, neuronal cells, endothelial cells, and cardiomyocytes. At the same time, adipose tissue can be harvested by a minimally invasive procedure, which makes it a promising source of adult stem cells. Therefore, it is believed that ASCs may become an alternative to the currently available adult stem cells (e.g. bone marrow stromal cells) for potential use in regenerative medicine. In this review, we present the basic information about the field of adipose-derived stem cells and their potential use in various applications.

引用

页码：236 / 257

页数：22

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