Treatment of a septic shock due to multiresistant Acinetobacter baumannii with tigecycline in combination

被引：12

作者：

Leclerc, T. ^{[1
]}

Perez, J. -P. ^{[1
]}

Debien, B. ^{[1
]}

Clapson, P. ^{[1
]}

Lenoir, B. ^{[1
]}

机构：

[1] HIA Percy, Serv Anethesie Reanimat, F-92141 Clamart, France

来源：

ANNALES FRANCAISES D ANESTHESIE ET DE REANIMATION | 2007年 / 26卷 / 12期

关键词：

tigecycline; Acinetobacter baumannii; septic shock; pneumonia;

D O I：

10.1016/j.annfar.2007.08.015

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

We report a case of pulmonary and bloodstream infection due to multiresistant Acinetobacter baumannii six days after a severe trauma. Clinical condition transiently improved following antimicrobial treatment with ticarcillin-clavulanate and rifampicin. However, a septic shock developed on the fourth day due to the emergence of a strain only sensible to cotrimoxazole, colistin and tigecycline. Cure was achieved after a two week treatment with piperacillin-tazobactam, cotrimoxazole and tigecycline. This case shows that combined antimicrobial therapy including tigecycline can be relevant in some severe pulmonary infections due to multiresistant A. baumannii. (C) 2007 Elsevier Masson SAS. Tous droits reserves.

引用

页码：1056 / 1058

页数：3

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