Synthesis of new homo and heterodimers of 2′,3′-dideoxyinosine (ddI) using ester linkages

被引：3
作者：
Mohamed, LA
Taourirte, M
Rochdi, A
Lazrek, HB
Vasseur, JJ
Engels, JW
Pannecouque, C
De Clercq, E
机构：
[1] Fac Sci, Chim Bioorgan Lab, Marrakech 40000, Morocco
[2] Fac Sci & Tech Gueliz, Marrakech, Morocco
[3] Univ Montpellier 2, Fac Sci, Lab Chim Organ Biomol Synth, F-34095 Montpellier 5, France
[4] Goethe Univ Frankfurt, Inst Organ Chem & Chem Biol, D-6000 Frankfurt, Germany
[5] Katholieke Univ Leuven, Rega Inst, B-3000 Louvain, Belgium
来源：
NUCLEOSIDES NUCLEOTIDES & NUCLEIC ACIDS | 2003年 / 22卷 / 5-8期
关键词：
dimers; ddI; AZT; d4T;
D O I：
10.1081/NCN-120022664
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
A series of new homo and heterodimers of ddI has been synthesized. A glutarate diester spacer was used to covalently couple ddI onto ddI, AZT or d4T.
引用
收藏
页码：829 / 831
页数：3
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