One new nucleoside and three furanpentanone derivatives from the aerial part of Rubia cordifolia L

被引:3
作者
He, Dong-Bing [1 ]
Bai, Xue [3 ]
Ma, Yu-Han [1 ]
Qin, Hai-Jun [1 ]
Wu, Yi-Bing [1 ]
Lv, Dong-Jin [4 ]
Mei, Ren-Qiang [2 ]
机构
[1] Hefei China Resources Shenlu Pharmaceut Co, Hefei 230601, Anhui, Peoples R China
[2] Kunming Inst Bot, Chinese Acad Sci, Resources West China, Kunming 650201, Yunnan, Peoples R China
[3] Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Yunnan, Peoples R China
[4] Kunming Med Univ, Affiliated Hosp 3, Dept Med Oncol, Kunming 650118, Yunnan, Peoples R China
关键词
Rubia cordifolia; Secondary metabolites; NO production inhibition; A-C; ROOTS; ANTHRAQUINONES; CYTOTOXICITY; CONSTITUENTS;
D O I
10.1016/j.phytol.2020.11.009
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
One new nucleoside 1 and three new furanpentone derivatives 2-4 were isolated from the aerial part of Rubia cordifolia. Their structures were established using spectroscopic methods. Compounds 1 and 4 exhibited inhibition of NO production with IC50 values of 27.5 and 19.8 mu M, respectively.
引用
收藏
页码:125 / 128
页数:4
相关论文
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