Renal cell carcinoma to haemangioblastoma metastasis: A rare manifestation of Von Hippel-Lindau syndrome

被引：6
|
作者：
Dessauvagie, Benjamin F. [1 ]
Wong, G. [2 ]
Robbins, P. D. [1 ]
机构：
[1] QEII Med Ctr, PathWest Lab Med, Dept Tissue Pathol, Perth, WA 6009, Australia
[2] Sir Charles Gairdner Hosp, QEII Med Ctr, State Neurosurg Serv, Nedlands, WA 6009, Australia
来源：
JOURNAL OF CLINICAL NEUROSCIENCE | 2015年 / 22卷 / 01期
关键词：
Haemangioblastoma; Metastasis; Renal cell carcinoma; Tumour-to-tumour metastasis; Von Hippel-Lindau syndrome; OF-THE-LITERATURE; CEREBELLAR HEMANGIOBLASTOMA; SPINAL-CORD; DISEASE;
D O I：
10.1016/j.jocn.2014.04.024
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
Brain metastases are the most common intracranial malignancy in adults and may occasionally deposit within a pre-existing primary brain neoplasm. We describe, in two directly related family members, the rare occurrence of renal cell carcinoma (RCC) metastasis to haemangioblastoma (HB) in the context of Von Hippel Lindau syndrome. Detection of this phenomenon can be marred by histological overlap between RCC and HB and therefore careful histological examination, and consideration of supportive immunohistochemistry, is required when examining all HB resections. Metastatic RCC to HB upstages a primary RCC and is clinically diagnostic of Von Hippel Lindau syndrome. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：215 / 218
页数：4
相关论文
共 50 条
  • [31] Von Hippel-Lindau protein signalling in clear cell renal cell carcinoma
    Liao, Chengheng
    Hu, Lianxin
    Zhang, Qing
    NATURE REVIEWS UROLOGY, 2024, 21 (11) : 662 - 675
  • [32] Clear Cell Papillary Renal Cell Carcinoma in Von Hippel-Lindau Disease
    Rao, P.
    Monzon, F. A.
    Jonasch, E.
    Czerniak, B. A.
    Tamboli, P.
    LABORATORY INVESTIGATION, 2012, 92 : 236A - 236A
  • [33] Clear Cell Papillary Renal Cell Carcinoma in Von Hippel-Lindau Disease
    Rao, P.
    Monzon, F. A.
    Jonasch, E.
    Czerniak, B. A.
    Tamboli, P.
    MODERN PATHOLOGY, 2012, 25 : 236A - 236A
  • [34] Establishment and characterization of a renal cell carcinoma line from a patient with von Hippel-Lindau syndrome
    Morash, BA
    Lee, CLY
    Rowden, G
    Riddell, DC
    Guernsey, DL
    CANCER GENETICS AND CYTOGENETICS, 1997, 96 (01) : 50 - 57
  • [35] Von-Hippel-Lindau-SyndromVon Hippel-Lindau syndrome
    W. Reith
    H. Körner
    Der Radiologe, 2013, 53 : 1104 - 1106
  • [36] Clear cell renal carcinoma presenting as a bleeding cyst in pregnancy: inaugural manifestation of a von Hippel-Lindau disease
    Simon, I.
    Rorive, S.
    Kirkpatrick, C.
    Rourneguere, T.
    Nortier, J. L.
    CLINICAL NEPHROLOGY, 2008, 69 (03) : 224 - 228
  • [37] The von Hippel-Lindau tumor suppressor protein and clear cell renal carcinoma
    Kaelin, William G., Jr.
    CLINICAL CANCER RESEARCH, 2007, 13 (02) : 680S - 684S
  • [38] Cauda Equina Syndrome as First Manifestation of von Hippel-Lindau Disease
    Chen, Xinji
    Xu, Guokang
    Bi, Qing
    Huang, Yazeng
    Shao, Haiyu
    Jin, Mengran
    Mesfin, Addisu
    Zhang, Jun
    WORLD NEUROSURGERY, 2019, 125 : 316 - 319
  • [39] Von Hippel-Lindau Syndrome and Steroid Cell Tumour of the Ovary: A Rare Association
    Datta, Amrita
    Thomas, Vinotha
    Sebastian, Ajit
    Thomas, Anitha
    Chandy, Rachel George
    Peedicayil, Abraham
    Kumar, Ramani Manoj
    Simon, Betty
    INDIAN JOURNAL OF GYNECOLOGIC ONCOLOGY, 2019, 17 (04)
  • [40] Copy Number Profiling in Von Hippel-Lindau Disease Renal Cell Carcinoma
    Shuib, Salwati
    Wei, Wenbin
    Sur, Hariom
    Morris, Mark R.
    McMullan, Dominic
    Rattenberry, Eleanor
    Meyer, Esther
    Maxwell, Patrick H.
    Kishida, Takeshi
    Yao, Masahiro
    Latif, Farida
    Maher, Eamonn R.
    GENES CHROMOSOMES & CANCER, 2011, 50 (07): : 479 - 488
12345