Renal cell carcinoma to haemangioblastoma metastasis: A rare manifestation of Von Hippel-Lindau syndrome

被引：6

作者：

Dessauvagie, Benjamin F. ^{[1
]}

Wong, G. ^{[2
]}

Robbins, P. D. ^{[1
]}

机构：

[1] QEII Med Ctr, PathWest Lab Med, Dept Tissue Pathol, Perth, WA 6009, Australia

[2] Sir Charles Gairdner Hosp, QEII Med Ctr, State Neurosurg Serv, Nedlands, WA 6009, Australia

来源：

JOURNAL OF CLINICAL NEUROSCIENCE | 2015年 / 22卷 / 01期

关键词：

Haemangioblastoma; Metastasis; Renal cell carcinoma; Tumour-to-tumour metastasis; Von Hippel-Lindau syndrome; OF-THE-LITERATURE; CEREBELLAR HEMANGIOBLASTOMA; SPINAL-CORD; DISEASE;

D O I：

10.1016/j.jocn.2014.04.024

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Brain metastases are the most common intracranial malignancy in adults and may occasionally deposit within a pre-existing primary brain neoplasm. We describe, in two directly related family members, the rare occurrence of renal cell carcinoma (RCC) metastasis to haemangioblastoma (HB) in the context of Von Hippel Lindau syndrome. Detection of this phenomenon can be marred by histological overlap between RCC and HB and therefore careful histological examination, and consideration of supportive immunohistochemistry, is required when examining all HB resections. Metastatic RCC to HB upstages a primary RCC and is clinically diagnostic of Von Hippel Lindau syndrome. (C) 2014 Elsevier Ltd. All rights reserved.

引用

页码：215 / 218

页数：4

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