The role of interleukin-1 and the inflammasome in gout - Implications for therapy

被引：171
作者：
Pope, Richard M.
Tschopp, Juerg
机构：
[1] Northwestern Univ, Feinberg Sch Med, Evanston, IL 60208 USA
[2] Jesse Brown VA Med Ctr, Chicago, IL USA
[3] Univ Lausanne, CH-1066 Epalinges, Switzerland
来源：
ARTHRITIS AND RHEUMATISM | 2007年 / 56卷 / 10期
关键词：
MONOSODIUM URATE CRYSTALS; MUCKLE-WELLS-SYNDROME; MESSENGER-RNA; GENE; MONOCYTES; CASPASES; IL-1; PATHOGENESIS; INHIBITION; ACTIVATION;
D O I：
10.1002/art.22938
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
[No abstract available]
引用
收藏
页码：3183 / 3188
页数：8
相关论文
共 33 条
[1]   Association of mutations in the NALP3/CIAS1/PYPAF1 gene with a broad phenotype including recurrent fever, cold sensitivity, sensorineural deafness, and AA amyloidosis [J].
Aganna, E ;
Martinon, F ;
Hawkins, PN ;
Ross, JB ;
Swan, DC ;
Booth, DR ;
Lachmann, HJ ;
Gaudet, R ;
Woo, P ;
Feighery, C ;
Cotter, FE ;
Thome, M ;
Hitman, GA ;
Tschopp, J ;
McDermott, MF .
ARTHRITIS AND RHEUMATISM, 2002, 46 (09) :2445-2452
[2]   NALP3 forms an IL-lβ-Processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder [J].
Agostini, L ;
Martinon, F ;
Burns, K ;
McDermott, MF ;
Hawkins, PN ;
Tschopp, J .
IMMUNITY, 2004, 20 (03) :319-325
[3]   INFORMATION FOR THE DORSAL VENTRAL PATTERN OF THE DROSOPHILA EMBRYO IS STORED AS MATERNAL MESSENGER-RNA [J].
ANDERSON, KV ;
NUSSLEINVOLHARD, C .
NATURE, 1984, 311 (5983) :223-227
[4]   New insights into the mechanism of IL-1β maturation [J].
Burns, K ;
Martinon, F ;
Tschopp, J .
CURRENT OPINION IN IMMUNOLOGY, 2003, 15 (01) :26-30
[5]   MyD88-dependent IL-1 receptor signaling is essential for gouty inflammation stimulated by monosodium urate crystals [J].
Chen, Chun-Jen ;
Shi, Yan ;
Hearn, Arron ;
Fitzgerald, Kate ;
Golenbock, Douglas ;
Reed, George ;
Akira, Shizuo ;
Rock, Kenneth L. .
JOURNAL OF CLINICAL INVESTIGATION, 2006, 116 (08) :2262-2271
[6]   COLCHICINE ALTERS THE QUANTITATIVE AND QUALITATIVE DISPLAY OF SELECTINS ON ENDOTHELIAL-CELLS AND NEUTROPHILS [J].
CRONSTEIN, BN ;
MOLAD, Y ;
REIBMAN, J ;
BALAKHANE, E ;
LEVIN, RI ;
WEISSMANN, G .
JOURNAL OF CLINICAL INVESTIGATION, 1995, 96 (02) :994-1002
[7]   URATE CRYSTALS STIMULATE PRODUCTION OF TUMOR-NECROSIS-FACTOR-ALPHA FROM HUMAN BLOOD MONOCYTES AND SYNOVIAL-CELLS - CYTOKINE MESSENGER-RNA AND PROTEIN KINETICS, AND CELLULAR-DISTRIBUTION [J].
DIGIOVINE, FS ;
MALAWISTA, SE ;
THORNTON, E ;
DUFF, GW .
JOURNAL OF CLINICAL INVESTIGATION, 1991, 87 (04) :1375-1381
[8]  
DIGIOVINE FS, 1987, J IMMUNOL, V138, P3213
[9]   New mutations of CIAS1 that are responsible for Muckle-Wells syndrome and familial cold urticaria:: A novel mutation underlies both syndromes [J].
Dodé, C ;
Le Dû, N ;
Cuisset, L ;
Letourneur, F ;
Berthelot, JM ;
Vaudour, G ;
Meyrier, A ;
Watts, RA ;
Scott, DGI ;
Nicholls, A ;
Granel, B ;
Frances, C ;
Garcier, F ;
Edery, P ;
Boulinguez, S ;
Domergues, JP ;
Delpech, M ;
Grateau, G .
AMERICAN JOURNAL OF HUMAN GENETICS, 2002, 70 (06) :1498-1506
[10]   Toll-like receptors: From the discovery of NFKB to new insights into transcriptional regulations in innate immunity [J].
Doyle, Sarah L. ;
O'Neill, Luke A. J. .
BIOCHEMICAL PHARMACOLOGY, 2006, 72 (09) :1102-1113
1234