Comparison of the analytic sensitivities of a recombinant immunoblot assay and the radioimmune precipitation assay for the detection of antibodies to Trypanosoma cruzi in patients with Chagas disease

被引：7
|
作者：
Shah, Dinesh O. [1 ]
Chang, Chi-Deu [1 ]
Cheng, Kevin Y. [1 ]
Salbilla, Vince A. [1 ]
Adya, Neeraj [1 ]
Marchlewicz, Benedict A. [1 ]
Kirchhoff, Louis V. [2 ,3 ]
机构：
[1] Abbott Labs, Abbott Diagnost Div, Emerging Pathogens & Infect Dis R&D, Abbott Pk, IL 60064 USA
[2] Univ Iowa, Dept Internal Med, Iowa City, IA 52292 USA
[3] Univ Iowa, Dept Epidemiol, Iowa City, IA 52292 USA
来源：
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2010年 / 67卷 / 04期
关键词：
Chagas disease; Trypanosoma cruzi; Immunoblot assay; Radioimmune precipitation assay; RIPA; Analytic sensitivity; UNITED-STATES; DIAGNOSIS; ANTIGENS;
D O I：
10.1016/j.diagmicrobio.2010.03.013
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
The diagnosis of chronic Chagas disease usually is made by detecting antibodies to Trypanosoma cruzi, the protozoan parasite that causes this illness. A highly sensitive and specific immunoblot assay developed by us showed a higher analytic sensitivity than the radioimmune precipitation assay, which is used widely as a confirmatory test. (C) 2010 Elsevier Inc. All rights reserved.
引用
收藏
页码：402 / 405
页数：4
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