Chikungunya virus: clinical aspects and treatment - A Review

被引:98
作者
da Cunha, Rivaldo V. [1 ,2 ]
Trinta, Karen S. [3 ]
机构
[1] Fundacao Oswaldo Cruz, Campo Grande, MS, Brazil
[2] Univ Fed Mato Grosso do Sul, Fac Med, Campo Grande, MS, Brazil
[3] Fundacao Oswaldo Cruz, Bio Manguinhos, Rio De Janeiro, RJ, Brazil
来源
MEMORIAS DO INSTITUTO OSWALDO CRUZ | 2017年 / 112卷 / 08期
关键词
chikungunya; clinical aspects; treatment; diagnosis; review; REUNION ISLAND; EPIDEMIOLOGY; MANIFESTATIONS; PATHOGENESIS; ARBOVIRUSES; OUTBREAK; FEATURES; DISEASE; FEVER;
D O I
10.1590/0074-02760170044
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Chikungunya is a severe and debilitating disease. Currently, Brazil is experiencing an epidemic caused by three arboviruses, which has changed the way health professionals have diagnosed and treated infected patients. The difficulty of diagnosis and the lack of a protocol for patient treatment, which fits Brazilian health system models, have made it difficult to manage this disease. It is necessary to implement a multidisciplinary network of patient care, in which primary care units play the main role. This review aims to present current information regarding the clinical aspects and treatment of Chikungunya virus infection.
引用
收藏
页码:523 / 531
页数:9
相关论文
共 48 条
[11]   Seroprevalence of Chikungunya Virus in a Rural Community in Brazil [J].
Cunha, Rivaldo V. ;
Trinta, Karen S. ;
Montalbano, Camila A. ;
Sucupira, Michel V. F. ;
de Lima, Maricelia M. ;
Marques, Erenilde ;
Romanholi, Izilyanne H. ;
Croda, Julio .
PLOS NEGLECTED TROPICAL DISEASES, 2017, 11 (01)
[12]   Multidisciplinary prospective study of mother-to-child chikungunya virus infections on the Island of La Reunion [J].
Gerardin, Patrick ;
Barau, Georges ;
Michault, Alain ;
Bintner, Marc ;
Randrianaivo, Hanitra ;
Choker, Ghassan ;
Lenglet, Yann ;
Touret, Yasmina ;
Bouveret, Anne ;
Grivard, Philippe ;
Le Roux, Karin ;
Blanc, Severine ;
Schuffenecker, Isabelle ;
Couderc, Therese ;
Arenzana-Seisdedos, Fernando ;
Lecuit, Marc ;
Robillard, Pierre-Yves .
PLOS MEDICINE, 2008, 5 (03) :413-423
[13]  
HARRISON VR, 1971, J IMMUNOL, V107, P643
[14]  
Hassing RJ, 2010, EUROSURVEILLANCE, V15, P22
[15]   Immuno-biology of Chikungunya and implications for disease intervention [J].
Kam, Yiu-Wing ;
Ong, Edward K. S. ;
Renia, Laurent ;
Tong, Joo-Chuan ;
Ng, Lisa F. P. .
MICROBES AND INFECTION, 2009, 11 (14-15) :1186-1196
[16]   Seroprevalence of Anti-Chikungunya Virus Antibodies in Children and Adults in Managua, Nicaragua, After the First Chikungunya Epidemic, 2014-2015 [J].
Kuan, Guillermina ;
Ramirez, Stephania ;
Gresh, Lionel ;
Ojeda, Sergio ;
Melendez, Marlon ;
Sanchez, Nery ;
Collado, Damaris ;
Garcia, Nadezna ;
Mercado, Juan Carlos ;
Gordon, Aubree ;
Balmaseda, Angel ;
Harris, Eva .
PLOS NEGLECTED TROPICAL DISEASES, 2016, 10 (06)
[17]   Chikungunya virus outbreak in Kerala, India, 2007: a seroprevalence study [J].
Kumar, Narendran Pradeep ;
Suresh, Abidha ;
Vanamail, Perumal ;
Sabesan, Shanmugavelu ;
Krishnamoorthy, Kalianna Gounder ;
Mathew, Jacob ;
Jose, Varakilparambil Thomas ;
Jambulingam, Purushothaman .
MEMORIAS DO INSTITUTO OSWALDO CRUZ, 2011, 106 (08) :912-916
[18]   Chikungunya virus, epidemiology, clinics and phylogenesis: A review [J].
Lo Presti, Alessandra ;
Lai, Alessia ;
Cella, Eleonora ;
Zehender, Gianguglielmo ;
Ciccozzi, Massimo .
ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE, 2014, 7 (12) :925-932
[19]  
Lopes N, 2014, REV PAN-AMAZ SAUDE, V5, P10, DOI [DOI 10.5123/S2176-62232014000300007, 10.5123/s2176-62232014000300007]
[20]   Cellular and molecular mechanisms of chikungunya pathogenesis [J].
Lum, Fok-Moon ;
Ng, Lisa F. P. .
ANTIVIRAL RESEARCH, 2015, 120 :165-174