Large cell neuroendocrine carcinoma of the endometrium: An extremely uncommon diagnosis, but worth the efforts

被引：24

作者：

Deodhar, Kedar K. ^{[1
]}

Kerkar, R. A. ^{[2
]}

Suryawanshi, Pallavi ^{[1
]}

Menon, Hari ^{[3
]}

Menon, Santosh ^{[1
]}

机构：

[1] Tata Mem Hosp, Dept Pathol, Bombay 400012, Maharashtra, India

[2] Tata Mem Hosp, Dept Surg Gynecol Oncol, Bombay 400012, Maharashtra, India

[3] Tata Mem Hosp, Dept Med Oncol, Bombay 400012, Maharashtra, India

来源：

JOURNAL OF CANCER RESEARCH AND THERAPEUTICS | 2011年 / 7卷 / 02期

关键词：

Endometrium; large-cell neuroendocrine carcinoma; neuroendocrine carcinoma;

D O I：

10.4103/0973-1482.82942

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Neuroendocrine carcinomas (NEC) of the female genital tract are aggressive and uncommon tumors. They usually involve the cervix and ovary, and are seen very rarely in the endometrium. The overwhelming majority of endometrial NECs are of conventional small cell type (up to 60 cases). Only seven cases of large cell type NEC of the endometrium have been reported. We report a case of large-cell neuroendocrine carcinoma (LCNEC) of the endometrium in a 70-year-old female. The case is described for its rarity and shows that a high index of suspicion can help the pathologist to use immunohistochemistry and in turn help in selection of appropriate chemotherapy.

引用

页码：211 / 213

页数：3

共 8 条

[1] Small cell carcinomas and large cell neuroendocrine carcinomas of the endometrium and cervix: Polypoid tumors and those arising in polyps may have a favorable prognosis
Albores-Saavedra, Jorge
Martinez-Benitez, Braulio
Luevano, Eduardo
[J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 2008, 27 (03) : 333 - 339
[2] Small cell neuroendocrine carcinoma of the endometrium and laparoscopic staging: a clinicopathologic study of a case and a brief review of the literature
Bige, O.
Saatli, B.
Secil, M.
Koyuncuoglu, M.
Saygili, U.
[J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2008, 18 (04) : 838 - U5
[3] Brambilla E., 2004, World Health Organization Classification of Tumours Pathology and Genetics of Tumours of the Lung, Pleura, Thymus and Heart, P45
[4] Eichhorn J H, 2001, Am J Clin Pathol, V115 Suppl, pS94
[5] SMALL-CELL CARCINOMA OF THE ENDOMETRIUM - A CLINICOPATHOLOGICAL STUDY OF 16 CASES
HUNTSMAN, DG
CLEMENT, PB
GILKS, CB
SCULLY, RE
[J]. AMERICAN JOURNAL OF SURGICAL PATHOLOGY, 1994, 18 (04) : 364 - 375
[6] Small cell carcinoma of the endometrium: report of three cases and literature review
Katahira, A
Akahira, J
Niikura, H
Ito, K
Moriya, T
Matsuzawa, S
Makinoda, S
Oda, T
Fujiwara, K
Yaegashi, N
[J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2004, 14 (05) : 1018 - 1023
[7] Combined large cell neuroendocrine and endometrioid carcinoma of the endometrium
Mulvany, Nicholas J.
Allen, David G.
[J]. INTERNATIONAL JOURNAL OF GYNECOLOGICAL PATHOLOGY, 2008, 27 (01) : 49 - 57
[8] Large cell neuroendocrine carcinoma with sarcomatous changes of the endometrium: A case report with immunohistochemical studies and molecular genetic study of KIT and PDGFRA
Terada, Tadashi
[J]. PATHOLOGY RESEARCH AND PRACTICE, 2010, 206 (06) : 420 - 425

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