Revisiting paracetamol in a quest for new co-crystals

被引:24
|
作者
Andre, Vania [1 ]
da Piedade, M. Fatima M. [1 ,2 ]
Teresa Duarte, M. [1 ]
机构
[1] Univ Tecn Lisboa, Ctr Quim Estrutural, Dept Engn Quim, Inst Super Tecn, P-1049001 Lisbon, Portugal
[2] FCUL, Dept Quim & Bioquim, P-1749016 Lisbon, Portugal
来源
CRYSTENGCOMM | 2012年 / 14卷 / 15期
关键词
ORTHORHOMBIC PARACETAMOL; P-HYDROXYACETANILIDE; FORM-III; MECHANICAL-PROPERTIES; VARIABLE-TEMPERATURE; NEUTRON-DIFFRACTION; DIRECT COMPRESSION; MONOCLINIC FORM; BINARY-MIXTURES; HYDROGEN-BONDS;
D O I
10.1039/c2ce25307k
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Paracetamol, one of the most widely available analgesics, is long known, but still a challenge for crystal engineers. Herein we discuss a new polymorphic form of the morpholine solvate and present two novel co-crystals with lone pair heterocycles.
引用
收藏
页码:5005 / 5014
页数:10
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