A Clinical Trial with Brazilian Arnica (Solidago chilensis Meyen) Glycolic Extract in the Treatment of Tendonitis of Flexor and Extensor Tendons of Wrist and Hand

被引：10

作者：

da Silva, Ary Gomes ^{[1
]}

Machado, Elbe Rodrigues ^{[2
]}

de Almeida, Leonardo Mendes ^{[2
]}

Menezes Nunes, Ricardo Marcelo ^{[2
]}

Pena Giesbrecht, Patricia Caldeira ^{[3
]}

Costa, Regina Mamed ^{[4
]}

Costa, Helber B. ^{[5
]}

Romao, Wanderson ^{[5
,6
]}

Kuster, Ricardo Machado ^{[7
]}

机构：

[1] UVV, Lab Funct Ecol, BR-29102770 Boa Vista, ES, Brazil

[2] Univ Vila Velha UVV ES, Dept Pharm, Vila Velha, ES, Brazil

[3] Univ Vila Velha UVV ES, Dept Physiotherapy, Vila Velha, ES, Brazil

[4] UFES, Doctoral Program Biotechnol, Northeastern Web Biotechnol RENORBIO, Sao Paulo, Brazil

[5] UFES, Dept Chem, Petrole & Forens Lab, Sao Paulo, Brazil

[6] IFES ES, Fed Inst Espirito Santo, Vila Velha, Brazil

[7] Fed Univ Rio de Janeiro IPPN UFRJ, Inst Nat Prod Res, Lab Phytochem Med Plants, Rio De Janeiro, Brazil

来源：

PHYTOTHERAPY RESEARCH | 2015年 / 29卷 / 06期

关键词：

antiinflammatory; antinociception activity; repetitive strain injury; pain; phytotherapy; Asteraceae; MURINE MODEL; DITERPENE; SESQUITERPENE; INFLAMMATION; DERIVATIVES; ANTIOXIDANT; PAIN;

D O I：

10.1002/ptr.5323

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

One of the Brazilian arnicas, Solidago chilensis Meyen, is a species of the Asteraceae family. This plant is known by this common name because it shares remarkably similar organoleptic properties with the genus Arnica L., also within the family Asteraceae. We examined the effectiveness of the S. chilensis fluid extract used externally for treating tendinitis of flexor and extensor tendons of wrist and hand in placebo-controlled double-blind clinical pharmacological studies. This study was approved by the Ethical Committee for Scientific Research in Human Beings at University Vila Velha-UVV. Two daily skin applications on the arm skin of a gel cream containing a 5% glycolic plant extract were administered to eight volunteers for 21days. Among the volunteers, one of their arms was used as the placebo group, and the other one was used as a test group. Statistical data analyses demonstrated a significant reduction in the perception of pain in the arms in the test group, when it was compared to those receiving only the placebo. Copyright (c) 2015 John Wiley & Sons, Ltd.

引用

页码：864 / 869

页数：6

共 1 条

[1] Evaluation of an Extract of Brazilian Arnica (Solidago chilensis Meyen, Asteraceae) in Treating Lumbago
da Silva, Ary G.
de Sousa, Carlos P. G.
Koehler, Jaeder
Fontana, Joelder
Christo, Alexandre G.
Guedes-Bruni, Rejan R.
PHYTOTHERAPY RESEARCH, 2010, 24 (02) : 283 - 287

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