Chemical Enhancement by Nanomaterials under X-ray Irradiation

被引：118

作者：

Cheng, Neal N. ^{[1
]}

Starkewolf, Zane ^{[1
]}

Davidson, R. Andrew ^{[1
]}

Sharmah, Arjun ^{[1
]}

Lee, Changju ^{[1
]}

Lien, Jennifer ^{[1
]}

Guo, Ting ^{[1
]}

机构：

[1] Univ Calif Davis, Dept Chem, Davis, CA 95616 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2012年 / 134卷 / 04期

基金：

美国国家科学基金会;

关键词：

NANOSCALE ENERGY DEPOSITION; GOLD NANOPARTICLES; DISMUTATION; CATALYSTS; RADICALS;

D O I：

10.1021/ja210239k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We report here a new phenomenon of dynamic enhancement of chemical reactions by nanomaterials under hard X-ray irradiation. The nanomaterials were gold and platinum nanoparticles, and the chemical reaction employed was the hydroxylation of coumarin carboxylic acid. The reaction yield was enhanced 2000 times over that predicted on the basis of the absorption of X-rays only by the nanoparticles, and the enhancement was found for the first time to depend on the X-ray dose rate. The maximum turnover frequency was measured at 1 x 10(-4) s(-1) Gy(-1). We call this process chemical enhancement, which is defined as the increased yield of a chemical reaction due to the chemical properties of the added materials. The chemical enhancement described here is believed to be ubiquitous and may significantly alter the outcome of chemical reactions under X-ray irradiation with the assistance of nanomaterials.

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页码：1950 / 1953

页数：4

相关论文

共 30 条

[1] Formation of peroxy radicals from OH-toluene adducts and O2 [J].

Bohn, B .

JOURNAL OF PHYSICAL CHEMISTRY A, 2001, 105 (25) :6092-6101

[2] Evaluation of cytotoxicity and radiation enhancement using 1.9 nm gold particles: potential application for cancer therapy [J].

Butterworth, K. T. ;

Coulter, J. A. ;

Jain, S. ;

Forker, J. ;

McMahon, S. J. ;

Schettino, G. ;

Prise, K. M. ;

Currell, F. J. ;

Hirst, D. G. .

NANOTECHNOLOGY, 2010, 21 (29)

[3] Gold Nanoparticles Enhancing Dismutation of Superoxide Radical by Its Bis(dithiocarbamato)copper(II) Shell [J].

Cao, Roberto, Jr. ;

Villalonga, Reynaldo ;

Diaz-Garcia, Alicia M. ;

Cao, Roberto ;

Rojo, Teofilo ;

Carmen Rodriguez-Argueelles, M. .

INORGANIC CHEMISTRY, 2011, 50 (11) :4705-4712

[4] Nanoscale energy deposition by x-ray absorbing nanostructures [J].

Carter, Joshua D. ;

Cheng, Neal N. ;

Qu, Yongquan ;

Suarez, George D. ;

Guo, Ting .

JOURNAL OF PHYSICAL CHEMISTRY B, 2007, 111 (40) :11622-11625

[5] Gold Nanoparticles as Radiation Sensitizers in Cancer Therapy [J].

Chithrani, Devika B. ;

Jelveh, Salomeh ;

Jalali, Farid ;

van Prooijen, Monique ;

Allen, Christine ;

Bristow, Robert G. ;

Hill, Richard P. ;

Jaffray, David A. .

RADIATION RESEARCH, 2010, 173 (06) :719-728

[6] The dosimetric feasibility of gold nanoparticle-aided radiation therapy (GNRT) via brachytherapy using low-energy gamma-/x-ray sources [J].

Cho, Sang Hyun ;

Jones, Bernard L. ;

Krishnan, Sunil .

PHYSICS IN MEDICINE AND BIOLOGY, 2009, 54 (16) :4889-4905

[7] Enhanced relaxation of nanoparticle-bound supercoiled DNA in X-ray radiation [J].

Foley, EA ;

Carter, JD ;

Shan, F ;

Guo, T .

CHEMICAL COMMUNICATIONS, 2005, (25) :3192-3194

[8]

Garcia H., 2011, Journal of the American Chemical Society, V133, P2218

[9] The use of gold nanoparticles to enhance radiotherapy in mice [J].

Hainfeld, JF ;

Slatkin, DN ;

Smilowitz, HM .

PHYSICS IN MEDICINE AND BIOLOGY, 2004, 49 (18) :N309-N315

[10] NOVEL GOLD CATALYSTS FOR THE OXIDATION OF CARBON-MONOXIDE AT A TEMPERATURE FAR BELOW 0-DEGREES-C [J].

HARUTA, M ;

KOBAYASHI, T ;

SANO, H ;

YAMADA, N .

CHEMISTRY LETTERS, 1987, (02) :405-408