Tandem Michael/intramolecular aldol reactions mediated by secondary amines, thiols and phosphines

被引：51
|
作者：
Dinon, F
Richards, E
Murphy, PJ [1 ]
Hibbs, DE
Hursthouse, MB
Abdul Malik, KM
机构：
[1] Univ Coll N Wales, Dept Chem, Bangor LL57 2UW, Gwynedd, Wales
[2] Univ Wales, Dept Chem, Cardiff CF1 3TB, S Glam, Wales
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 16期
基金：
英国工程与自然科学研究理事会;
关键词：
D O I：
10.1016/S0040-4039(99)00419-0
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The secondary amine mediated Baylis-Hillman reaction has been found to proceed via a tandem Michael addition/intramolecular aldol followed by a slow elimination step; it was also observed that similar processes can be effected using phosphines and thiols as mediators. (C) 1999 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：3279 / 3282
页数：4
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