Redosing Adeno-Associated Virus Gene Therapy to the Central Nervous System

被引：5
|
作者：
McElroy, Abigail [1 ,2 ]
Sena-Esteves, Miguel [1 ,2 ,3 ]
Arjomandnejad, Motahareh [1 ,2 ]
Keeler, Allison M. M. [1 ,2 ,4 ]
Gray-Edwards, Heather L. L. [1 ,2 ,5 ,6 ,7 ]
机构：
[1] UMass Chan Med Sch, Horae Gene Therapy Ctr, Worcester, MA USA
[2] UMass Chan Med Sch, Li Weibo Inst Rare Dis Res, Worcester, MA USA
[3] UMass Chan Med Sch, Dept Neurol, Worcester, MA USA
[4] UMass Chan Med Sch, Dept Pediat, Worcester, MA USA
[5] UMass Chan Med Sch, Dept Radiol, Worcester, MA USA
[6] UMass Chan Med Sch, Horae Gene Therapy Ctr, 368 Plantat St, Worcester, MA 01605 USA
[7] UMass Chan Med Sch, Li Weibo Inst Rare Dis Res, 368 Plantat St, Worcester, MA 01605 USA
来源：
HUMAN GENE THERAPY | 2022年 / 33卷 / 17-18期
关键词：
central nervous system; gene therapy; AAV; NEUTRALIZING ANTIBODIES; TRANSGENE EXPRESSION; SKELETAL-MUSCLE; ADULT MICE; BRAIN; AAV; VECTORS; DELIVERY; TURNOVER; ROUTES;
D O I：
10.1089/hum.2022.170
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
[No abstract available]
引用
收藏
页码：889 / 892
页数：4
相关论文
共 50 条
  • [11] Adeno-associated virus vector-mediated gene transfer to somatic cells in the central nervous system
    Klein, RL
    Mandel, RJ
    Muzyczka, N
    ADVANCES IN VIRUS RESEARCH, VOL 55, 2000, 55 : 507 - 528
  • [12] Adeno-Associated Virus Gene Therapy for Hemophilia
    Samelson-Jones, Benjamin J.
    George, Lindsey A.
    ANNUAL REVIEW OF MEDICINE, 2023, 74 : 231 - 247
  • [13] Adeno-associated virus for cancer gene therapy
    Ponnazhagan, S
    Curiel, DT
    Shaw, DR
    Alvarez, RD
    Siegal, GP
    CANCER RESEARCH, 2001, 61 (17) : 6313 - 6321
  • [14] Adeno-associated virus as a gene delivery system
    During, MJ
    ADVANCED DRUG DELIVERY REVIEWS, 1997, 27 (01) : 83 - 94
  • [15] Complement System Response to Adeno-Associated Virus Vector Gene Therapy
    Kropf, Elizabeth
    Markusic, David M.
    Majowicz, Anna
    Mingozzi, Federico
    Kuranda, Klaudia
    HUMAN GENE THERAPY, 2024, 35 (13-14) : 425 - 438
  • [16] Adeno-Associated Virus Serotype 9 Transduction in the Central Nervous System of Nonhuman Primates
    Samaranch, Lluis
    Salegio, Ernesto A.
    San Sebastian, Waldy
    Kells, Adrian P.
    Foust, Kevin D.
    Bringas, John R.
    Lamarre, Clementine
    Forsayeth, John
    Kaspar, Brian K.
    Bankiewicz, Krystof S.
    HUMAN GENE THERAPY, 2012, 23 (04) : 382 - 389
  • [17] Immune responses to central nervous system directed adeno-associated virus gene therapy: Does direct CNS delivery make a difference?
    Harkins, Ashley L.
    Ambegaokar, Prajakta P.
    Keeler, Allison M.
    NEUROTHERAPEUTICS, 2024, 21 (04)
  • [18] Recombinant adeno-associated virus vectors for gene therapy
    Conlon, TJ
    Flotte, TR
    EXPERT OPINION ON BIOLOGICAL THERAPY, 2004, 4 (07) : 1093 - 1101
  • [19] Engineering adeno-associated virus vectors for gene therapy
    Li, Chengwen
    Samulski, R. Jude
    NATURE REVIEWS GENETICS, 2020, 21 (04) : 255 - 272
  • [20] Adenovirus and adeno-associated virus as vectors for gene therapy
    Berns, KI
    Giraud, C
    DNA VACCINES: A NEW ERA IN VACCINOLOGY, 1995, 772 : 95 - 104
12345