Redosing Adeno-Associated Virus Gene Therapy to the Central Nervous System

被引：6

作者：

McElroy, Abigail ^{[1
,2
]}

Sena-Esteves, Miguel ^{[1
,2
,3
]}

Arjomandnejad, Motahareh ^{[1
,2
]}

Keeler, Allison M. M. ^{[1
,2
,4
]}

Gray-Edwards, Heather L. L. ^{[1
,2
,5
,6
,7
]}

机构：

[1] UMass Chan Med Sch, Horae Gene Therapy Ctr, Worcester, MA USA

[2] UMass Chan Med Sch, Li Weibo Inst Rare Dis Res, Worcester, MA USA

[3] UMass Chan Med Sch, Dept Neurol, Worcester, MA USA

[4] UMass Chan Med Sch, Dept Pediat, Worcester, MA USA

[5] UMass Chan Med Sch, Dept Radiol, Worcester, MA USA

[6] UMass Chan Med Sch, Horae Gene Therapy Ctr, 368 Plantat St, Worcester, MA 01605 USA

[7] UMass Chan Med Sch, Li Weibo Inst Rare Dis Res, 368 Plantat St, Worcester, MA 01605 USA

来源：

HUMAN GENE THERAPY | 2022年 / 33卷 / 17-18期

关键词：

central nervous system; gene therapy; AAV; NEUTRALIZING ANTIBODIES; TRANSGENE EXPRESSION; SKELETAL-MUSCLE; ADULT MICE; BRAIN; AAV; VECTORS; DELIVERY; TURNOVER; ROUTES;

D O I：

10.1089/hum.2022.170

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

[No abstract available]

引用

页码：889 / 892

页数：4

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