Formation of short, stable helices in aqueous solution by β-amino acid hexamers

被引：217

作者：

Appella, DH

Barchi, JJ ^{[1
]}

Durell, SR

Gellman, SH

机构：

[1] NCI, Med Chem Lab, Bethesda, MD 20892 USA

[2] NCI, Lab Expt & Computat Biol, Div Basic Sci, Bethesda, MD 20892 USA

[3] Univ Wisconsin, Dept Chem, Madison, WI 53706 USA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1999年 / 121卷 / 10期

关键词：

D O I：

10.1021/ja983918n

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：2309 / 2310

页数：2

共 43 条

[31] EXCHANGE KINETICS OF INDIVIDUAL AMIDE PROTONS IN N-15-LABELED HELICAL PEPTIDES MEASURED BY ISOTOPE-EDITED NMR [J].

ROHL, CA ;

BALDWIN, RL .

BIOCHEMISTRY, 1994, 33 (25) :7760-7767

[32] NMR SPECTROSCOPIC DETECTION OF CIS AND TRANS PEPTIDE-BONDS IN UNPROTECTED OLIGO-L-PROLINES [J].

ROTHE, M ;

ROTT, H .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION IN ENGLISH, 1976, 15 (12) :770-771

[33] beta-peptides: a surprise at every turn [J].

Seebach, D ;

Matthews, JL .

CHEMICAL COMMUNICATIONS, 1997, (21) :2015-2022

[34] beta-peptides: Synthesis by Arndt-Eistert homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy and by X-ray crystallography. Helical secondary structure of a beta-hexapeptide in solution and its stability towards pepsin [J].

Seebach, D ;

Overhand, M ;

Kuhnle, FNM ;

Martinoni, B ;

Oberer, L ;

Hommel, U ;

Widmer, H .

HELVETICA CHIMICA ACTA, 1996, 79 (04) :913-941

[35] β2- and β3-peptides with proteinaceous side chains:: Synthesis and solution structures of constitutional isomers, a novel helical secondary structure and the influence of solvation and hydrophobic interactions on folding [J].

Seebach, D ;

Abele, S ;

Gademann, K ;

Guichard, G ;

Hintermann, T ;

Jaun, B ;

Matthews, JL ;

Schreiber, JV .

HELVETICA CHIMICA ACTA, 1998, 81 (05) :932-982

[36] Probing the helical secondary structure of short-chain beta-peptides [J].

Seebach, D ;

Ciceri, PE ;

Overhand, M ;

Jaun, B ;

Rigo, D ;

Oberer, L ;

Hommel, U ;

Amstutz, R ;

Widmer, H .

HELVETICA CHIMICA ACTA, 1996, 79 (08) :2043-2066

[37] DE-NOVO DESIGN, SYNTHESIS, AND X-RAY CRYSTAL-STRUCTURES OF PYRROLINONE-BASED BETA-STRAND PEPTIDOMIMETICS [J].

SMITH, AB ;

GUZMAN, MC ;

SPRENGELER, PA ;

KEENAN, TP ;

HOLCOMB, RC ;

WOOD, JL ;

CARROLL, PJ ;

HIRSCHMANN, R .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1994, 116 (22) :9947-9962

[38] Secondary structure in oligomers of carbohydrate amino acids [J].

Smith, MD ;

Claridge, TDW ;

Tranter, GE ;

Sansom, MSP ;

Fleet, GWJ .

CHEMICAL COMMUNICATIONS, 1998, (18) :2041-2042

[39] THE CONFORMATIONS OF PROLINE-LINKED DONOR-ACCEPTOR SYSTEMS [J].

SNEDDON, SF ;

BROOKS, CL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1992, 114 (21) :8220-8225

[40] Solid phase synthesis and secondary structural studies of (1→5) amide-linked sialooligomers [J].

Szabo, L ;

Smith, BL ;

McReynolds, KD ;

Parrill, AL ;

Morris, ER ;

Gervay, J .

JOURNAL OF ORGANIC CHEMISTRY, 1998, 63 (04) :1074-1078

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